Results 1 to 10 of about 39 (38)

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Supplier Environmental Assessment in Sustainability Reporting: Evidence From Top ESG‐Performing Brazilian Firms

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the maturity of supplier‐related environmental disclosures in sustainability reports of top environmental, social, and governance (ESG)‐performing Brazilian companies. A content analysis of 67 reports from firms listed on the Corporate Sustainability Index (CSI) was conducted using the CRITIC method to weight disclosure ...
João Vyctor Brás dos Santos, Tiago F. A. C. Sigahi, Deoclécio Junior Cardoso da Silva, Silvia Regina Stuchi Cruz, Milena Pavan Serafim, Walter Leal Filho, Rosley Anholon   +6 more
wiley   +1 more source

Infant frontal alpha asymmetry predicts social attention and transdiagnostic risk for emotional reactivity

JCPP Advances, EarlyView.
Abstract Background Differences in Frontal Alpha Asymmetry (FAA), derived from the electroencephalogram (EEG), have been associated with approach‐withdrawal behavior, although inconsistently. The current study examined how early patterns of FAA during the first 2 years of life relate to various socioemotional characteristics (at 2 years) and ultimately
Viviane Valdes, Niccola Lutri, Haerin Chung, Charles A. Nelson   +3 more
wiley   +1 more source

Seed layer formation by deposition of micro‐crystallites on a revolving substrate. Part II: application to some nonlinear effects

Acta Crystallographica Section B, EarlyView.
A method of averaging the material coefficients of crystallites deposited at an angle onto a revolving substrate isapplied to effective nonlinear dielectric, piezoelectric and elastic constants, as well as linear pyroelectric coefficients, for triclinic crystals.The matrix method of averaging material coefficients of crystallites deposited at an angle ...
Arthur Ballato, John Ballato
wiley   +1 more source

Dynamic Trust Formation in AI‐Enabled Automation: A Longitudinal Case Study of an Advanced Driver Assistance System

Information Systems Journal, EarlyView.
ABSTRACT Artificial intelligence (AI)–enabled automation is often utilised in systems that perform human tasks. While useful, these technologies pose a risk of adverse consequences in the case of AI failures as they operate in open environments, learn and are subject to continuous updates.
Kari M. Koskinen, Niina Mallat, Virpi Kristiina Tuunainen, Antti Lyyra   +3 more
wiley   +1 more source

Regional Community Building in Hard Times: Communal and Functional Filtering at EU Borders During the COVID‐19 Pandemic

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Pandemics are times of closure. States typically restrict the entry of persons to protect their national communities from external health hazards. In this regard, the COVID‐19 pandemic presented the European Union (EU) with a severe challenge. We ask to what extent the border policies of EU member states during the pandemic supported regional ...
Christian Freudlsperger, Jana Lipps, Frank Schimmelfennig   +2 more
wiley   +1 more source

MAXTIA: A high‐throughput platform for rapid functional epitope mapping by kinetic screening of mutant libraries

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Accurate identification of epitope residues is essential for developing biopharmaceuticals and understanding the mechanisms of immune recognition. However, experimental approaches for residue‐level epitope mapping remain time‐consuming and labor‐intensive, while accurate computational prediction of protein–protein interfaces remains ...
Kihoon Kim, Ryo Matsunaga, Takanori Yokoo, Makoto Nakakido, Kouhei Tsumoto   +4 more
wiley   +1 more source

Molecular Epidemiology of Peste des Petits Ruminants Virus Circulating in Fat‐Tailed Sheep in Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study reports the molecular detection and genetic characterization of peste des petits ruminants virus in fat‐tailed sheep in Bangladesh. Phylogenetic analysis reveals transboundary lineage circulation, highlighting silent virus movement during high‐risk livestock trading periods and the need for strengthened regional surveillance.
Md. Arif Khan, Pronesh Dutta, Md. Kaisar Rahman, Abdullah‐Al Mamun, Jade K. Forwood, Shariful Islam, Ariful Islam   +6 more
wiley   +1 more source

Taxonomic complexity in the parasitic plant genus Cistanche: Evidence from phylogenomics

TAXON, Volume 75, Issue 4, August 2026.
Abstract “Desert hyacinths” (genus Cistanche) are striking parasitic plants of historical and cultural importance that include species traded widely for herbal medicine. Despite the need for robust taxonomy, the application of names in the genus remains confused.
Julie A. Hawkins, Benedikt G. Kuhnhäuser, Di Lei, Majed Aldughayman, Toral Shah, Dar Ben‐Natan, Lin‐fang Huang, Chris J. Thorogood   +7 more
wiley   +1 more source