Results 11 to 20 of about 4,430 (166)

Generation of functional noncanonical donor splice sites by +2T variants in breast cancer susceptibility genes: impact on clinical interpretation. [PDF]

open access: yesJ Pathol
Abstract Splicing dysregulation is a relevant mechanism of pathogenicity for variants in disease susceptibility genes. Variants affecting the critical intronic +1 and +2 GT nucleotides of the 5’ splice sites (5'ss) are generally strong indicators of pathogenicity.
Llinares-Burguet I   +7 more
europepmc   +2 more sources

Impact of APOE E4 on Glucose Tolerance and Lipid Profiles in Older Adults [PDF]

open access: yesAlzheimers Dement
Abstract Background Type 2 diabetes and elevated LDL cholesterol are reversible risk factors for Alzheimer's disease (AD), and the E4 allele of the APOE 4 gene is a genetic risk for AD. We have previously published that E4 status influences results on glucose tolerance test in those with early AD, and this project examines the relationship between ...
Thorali P   +3 more
europepmc   +2 more sources

Emerging Change: Exploring the New Economy Paradigm

open access: yesECONOMICS, 2022
This paper examines and ascertains the dominant and latent characteristics of the new economy post COVID-19. It acknowledges the far-reaching repercussions and long-term societal and economic impacts caused by COVID-19.
Rao K.V.Ch.Madhu Sudhana   +2 more
doaj   +1 more source

Crystal structure of (E)-4,4′-(but-2-ene-1,4-diyl)bis(2-methoxyphenol)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C18H20O4, was synthesized via the ruthenium-catalyzed alkene methathesis dimerization of eugenol. The whole molecule is generated by inversion symmetry; the center of inversion being located at the mid-point of the trans C=C bond. The
Kyle S. Knight, Patrick J. Carey
doaj   +1 more source

Turnover in EU Monetary Policy in a Crisis

open access: yesECONOMICS, 2023
The role of monetary policy has become increasingly important in recent years, as a range of economic challenges have emerged, affecting both developing and economically advanced countries.
Lebedeva Larysa, Shkuropadska Diana
doaj   +1 more source

The Impact of Macroprudential Policy Instruments on Financial Stability in Southern Europe

open access: yesNaše Gospodarstvo, 2022
This paper is a contribution to the body of research examining the impact of macroprudential policy instruments on financial stability. The following hypothesis was tested (H1): Macroprudential policy instruments (household borrowing costs; interbank ...
Lorenčič Eva, Festić Mejra
doaj   +1 more source

Macroeconomic Determinants Affecting Credit Risk in Central and Eastern Europe

open access: yesFolia Oeconomica Stetinensia, 2021
Research background: A number of microeconomic and macroeconomic variables affect credit risk. Macroeconomic factors are particularly significant for credit risk volatility.
Pluskota Anna
doaj   +1 more source

Spillover effects of unconventional monetary policy on capital markets in the shadow of the Eurozone: A sample of non-Eurozone countries

open access: yesReview of Economic Perspectives, 2020
The transmission mechanism has been dominated by direct monetary measures since the crisis of 2008. While the indirect impacts of the unconventional monetary instruments have not been fully explored yet.
Mészáros Mercédesz   +1 more
doaj   +1 more source

Time-Varying Housing Market Fluctuations: Evidence from the U.S. Housing Market

open access: yesReal Estate Management and Valuation, 2020
The objective of this paper is to investigate how the housing market and credit market factors contribute to US business and interest rate cycles in a time-varying transition probability modeling framework.
Ozdemir Dicle
doaj   +1 more source

¿Es la Teoría general una “teoría económica de la depresión”? Inestabilidad financiera y crisis en el pensamiento monetario de Keynes

open access: yesEl Trimestre Económico, 2021
En este artículo se reexaminan los escritos de Keynes desde Moneda y finanzas de la India (1913/1971) hasta la Teoría general de la ocupación, el interés y el dinero (1936a/1965), en particular, con un enfoque en la inestabilidad financiera.
Joerg Bibow
doaj   +1 more source

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