Results 121 to 130 of about 327,500 (191)

Transcription Factor AP-2 Regulatory Signatures in Breast Cancer

, 2007
PhDAP-2 transcription factors are highly conserved basic helix-span-helix proteins whose members ((x, ß, y, S and c) are crucial regulators of bryonic development. They also play an important role in human neoplasia.
Williams, Christopher M J, Williams, Christopher MJ   +1 more
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Characterizing the role of p21-Activated Kinase 3 (PAK3) in AP-1-induced transformation

, 2014
Includes bibliographical references.Previous studies identified p21-Activated Kinase 3 (PAK3), a serine/threonine kinase, as a potential AP-1 target gene.
Holderness-Parker, Nina Alison Victoria
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Alignment of HPV alpha E6 ORFs.

, 2013
The alignment of all 27 E6 ORFs tested in Figure 2 is shown. HPV types degrading p53 are shown at the top of the alignment and those not degrading p53 are shown at the bottom. The shaded region represents a proposed E6-AP binding domain [25], [26].
Gilles Travé (198525), Robert D. Burk (35757), Leiping Fu (361648), Zigui Chen (153298), Tutik Ristriani (361649), Murielle Masson (198518), Koenraad Van Doorslaer (30426)   +6 more
core   +1 more source

Multiple C-terminal Lysine residues target p53 for ubiquitin-proteasome-mediated degradation

, 2000
This work was supported by the Medical Research Council, the Biotechnology and Biological Research Council, and the Cancer Research Campaign. D.P.L. is a Gibb fellow of the Cancer Research Campaign.In normal cells, p53 is maintained at a low level by ...
Lain, Sonia, Lane, David P., T. Hay, Ronald, Hay, Ronald Thomas, Rodriguez, Manuel S, Desterro, Joana M P   +6 more
core   +1 more source

E6-mediated degradation of PDZ domain proteins is conserved in Drosophila.

, 2016
(A-T) apterous-Gal4 was used to express transgenes in the dorsal compartment of wing imaginal discs. In all images dorsal is to the left and ventral is to the right and dashed lines indicate the boundary between the two compartments.
Bing Zhang (129), Vanessa J. Auld (161774), Mojgan Padash Barmchi (2610196), Lawrence Banks (152980), Miranda Thomas (276625), Mary Gilbert (161752)   +5 more
core   +1 more source

Cell cycle control and its modulation in HPV infected cells

, 2010
A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
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Regulation of breast tumour cell survival by AP-2 transcription factors

, 2010
PhDAP-2 transcription factors are crucial regulators of embryonic development and also play important roles in human neoplasia. Over-expression of AP-2α and AP-2γ in primary breast cancer (BC) correlates with expression of two major breast markers ...
Chan, Ka Yi Viona
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E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer

Cancer Management and Research, 2019
Fee Klupp,1 Christina Giese,1 Niels Halama,2 Clemens Franz,1 Felix Lasitschka,3,4 Arne Warth,3 Thomas Schmidt,1 Matthias Kloor,5 Alexis Ulrich,1 Martin Schneider1 1Department of General, Visceral and Transplantation Surgery, University of Heidelberg ...
Klupp F, Giese C, Halama N, Franz C, Lasitschka F, Warth A, Schmidt T, Kloor M, Ulrich A, Schneider M   +9 more
doaj  

The Role of E6-Associated Protein in Estrogen Receptor Alpha Regulation

, 2010
The Estrogen Receptor alpha (ER alpha) is a multi-domain transcription factor that has been extensively studied due to its known involvement in breast cancer treatment and progression.
Catoe, Heath
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Detecção molecular do DNA e RNAm do HPV e sua aplicabilidade na triagem do câncer cervical [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011O câncer de colo uterino representa o segundo tipo de câncer mais comum entre as mulheres.
Martins, Toni Ricardo
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