Results 171 to 180 of about 327,500 (191)

Functional Calmodulin States Are Selected from an Electrostatically Tuned Free Energy Landscape. [PDF]

J Chem Inf Model
Tayhan B, Horozoglu S, Atilgan AR, Atilgan C.   +3 more
europepmc   +1 more source

SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS-STING. [PDF]

J Gen Virol
Chiu HP, Yeo YY, Lai TY, Hung CT, Kowdle S, Haas GD, Jiang S, Sun W, Lee B.   +8 more
europepmc   +1 more source

Shifts in Dissolved Organic Matter and Microbial Communities Under Continuous Cropping of <i>Aralia continentalis</i> Kitag.: A Comparative Study of 2-, 6-, and 12-Year Durations. [PDF]

Biology (Basel)
Liu Q, Guo X, Qu Y, Xing Y, Zheng J, Dong Z, Yu W, Zhang G.   +7 more
europepmc   +1 more source

Molecular Insights into HPV-Driven Cervical Cancer: Oncoproteins, Immune Evasion, and Epigenetic Modifications. [PDF]

Microorganisms
Pavelescu LA, Mititelu-Zafiu NL, Mindru DE, Vladareanu R, Curici A.   +4 more
europepmc   +1 more source

Emerging threat of Oropouche virus: Clinical features, experimental models, and virulence. [PDF]

Virulence
Alkan C, Ikegami T.
europepmc   +1 more source

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LRSAM1 E3 ubiquitin ligase promotes proteasomal clearance of E6-AP protein

Cellular Signalling, 2021
Numerous proteins participate and actively contribute to the various cellular mechanisms, where several of them are crucial for regular metabolism, including survival. Thus, to maintain optimal cellular physiology, cells govern protein quality control functions with the assistance of comprehensive actions of molecular chaperones, the ubiquitin ...
Ribhav, Mishra, Vibhuti, Joshi, Arun, Upadhyay, Ayeman, Amanullah, Ankur Rakesh, Dubey, Sarika, Singh, Vikash Kumar, Dubey, Krishna Mohan, Poluri, Nihar Ranjan, Jana, Amit, Mishra   +9 more
openaire   +2 more sources

E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity

Neurobiology of Aging, 2013
Protein aggregation and ordered fibrillar amyloid deposition inside and outside of the central nervous system cells is the common pathologic hallmark of most aging-related neurodegenerative disorders. Dominant mutations in the gene encoding superoxide dismutase 1 (SOD1) protein are linked to familial amyotrophic lateral sclerosis (ALS), a ...
Amit, Mishra, Megha, Maheshwari, Deepak, Chhangani, Noriko, Fujimori-Tonou, Fumito, Endo, Ajay Prakash, Joshi, Nihar Ranjan, Jana, Koji, Yamanaka   +7 more
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Ubiquitin, E6-AP, and Their Role in p53 Inactivation

Pharmacology & Therapeutics, 1998
Inactivation of the tumor suppressor protein p53 plays a key role in human carcinogenesis. Activation of the growth-suppressive properties of p53 by appropriate stress signals, including genotoxic stress, is generally accompanied by intracellular accumulation of the protein.
openaire   +2 more sources