Results 171 to 180 of about 129,891 (225)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Transcriptional modulation of the PI3K/AKT/mTOR signaling pathway mediated by HPV16 <i>E5</i>, <i>E6</i>, and <i>E7</i> oncogene expression in breast cancer. [PDF]

Explor Target Antitumor Ther
de Oliveira Isídio BE, Fontes PHB, da Silva GRP, Leão SL, de França São Marcos B, Simões IS, Barros EFG, Lussón DB, de Araujo GV, de Farias ID, de Melo KMTB, de Queiroz NL, da Silva SMS, Santos VEP, de Freitas AC.   +14 more
europepmc   +1 more source

Sleep disturbance as a transdiagnostic marker of children's mental health difficulties: A network analysis of item‐level associations between different types of sleep problems and different behavioural and emotional symptoms

JCPP Advances, EarlyView.
Abstract Background Sleep disturbances are widely considered to be a transdiagnostic feature of common behavioural and emotional difficulties in childhood, yet most studies treat sleep as a single construct. Where studies have explored specific sleep problems to psychopathology in children, these tend to only include behavioural or emotional ...
Alina A. Marinca, Julia E. Michalek, Alice M. Gregory, Afia Ali, Jennifer Y. F. Lau   +4 more
wiley   +1 more source

Oncolytic virus-mediated remodeling of tumor microenvironment enhances efficacy of an HPV16 E6/E7 mRNA vaccine in an HPV-positive tumor. [PDF]

Mol Ther Oncol
Johnson K, Wu W, Lim JJ, Tu N, Zhang SX.
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Ascelia‐Manganese‐Based MRI Contrast Agent (ACE‐MBCA) in Adult Subjects With and Without Hepatic Impairment

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Orally administered Ascelia‐manganese‐based contrast agent (ACE‐MBCA) is used for liver MRI, but its feasibility in patients with hepatic dysfunction remains unknown. Purpose To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of ACE‐MBCA in subjects without/with hepatic impairment.
Amit G. Singal, Eric Lawitz, Andreas Norlin, Nadilka Hettiarachchige, Thomas Bengtsson, Bachir Taouli   +5 more
wiley   +1 more source

Nicotiana glauca leaf extract exhibits synergistic antioxidant and anticancer activities revealed by phytochemical profiling and molecular docking. [PDF]

Sci Rep
Saeed MMH, Fayed SA, Hamdy R, Shalaby EA.   +3 more
europepmc   +1 more source

How Can Teams Benefit From AI Team Members? Exploring the Effect of Generative AI on Decision‐Making Processes and Decision Quality in Team–AI Collaboration

Journal of Organizational Behavior, EarlyView.
ABSTRACT Human teams with distributed knowledge can make high‐quality decisions but often fail due to decision‐making asymmetries. As AI team members become integrated collaborators, understanding how AI can reduce these decision‐making asymmetries is essential. However, little is known about how AI team members can reduce these asymmetries and whether
Désirée Zercher, Ekaterina Jussupow, Ivo Benke, Armin Heinzl   +3 more
wiley   +1 more source

DENV-4 infection suppresses transcription of DNA repair genes. [PDF]

Proc Natl Acad Sci U S A
Lamkin EN, Reich J, Victor JA, Guyette M, Kothandaraman N, Gupta V, Harding AT, Jordan TX, Gehrke L, Zhou P, tenOever B, Chatterjee N.   +11 more
europepmc   +1 more source

Targeting online sales through last‐mile delivery platform integration

Journal of Operations Management, Volume 71, Issue 2, Page 195-219, March 2025.
Abstract We analyze channel integration between a last‐mile delivery platform and a general merchandise retailer in two distinct stages: (1) platform delivery access (PDA), where the retailer continues to offer standard delivery through its own website but directs customers to the platform's website for new same‐day delivery; and (2) integrated ...
Kevin H. Park, Xiaodan Pan, Martin E. Dresner   +2 more
wiley   +1 more source

Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines. [PDF]

Blood Adv
Hodel AW, Noori T, Rudd-Schmidt JA, Williams SA, Sutton VR, Hoogenboom BW, Tam CS, Trapani JA, Voskoboinik I.   +8 more
europepmc   +1 more source