Results 61 to 70 of about 2,243,754 (245)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Melatonin Enhances Glutathione Peroxidase Activity and Improves Antioxidant Defense in Cryopreserved Ovarian Transplants: A Rat Model Study

Antioxidants
Background: Although ovarian cryopreservation is an essential strategy for fertility preservation, ischemia–reperfusion injury and oxidative stress can significantly compromise graft viability after transplantation.
Karla Krislane Alves Costa Monteiro, Luciana Lamarão Damous, Marcos Eiji Shiroma, José Antonio Orellana Turri, Ricardo dos Santos Simões, Manuel de Jesus Simões, José Cipolla-Neto, Lara Termini, Rinaldo Florencio-Silva, Peter Chedraui, Russel J. Reiter, Edmund Chada Baracat, Jose Maria Soares Junior   +12 more
doaj   +1 more source

Conservation-Restoration paradigm shift after disaster: the Graphic Documents case study

Conservar Património, 2017
With this paper we draw attention to the role of the disaster, leading to profound changes, to the paradigm shift in the intervention of conservation and restoration of graphic documents, based on the study of case studies from the two main disaster ...
Maria da Conceição Lopes Casanova
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Formation of green strength in hydraulically bonded refractory castables at room temperature

Open Ceramics
A sufficient green strength of refractory castables is necessary to avoid damage during demoulding and heating up of refractory linings and prefabricated parts.
J. Kasper, O. Krause, C. Dannert
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Patrones de distribución de las mariposas diurnas en Portugal (Lepidoptera, Papilionoidea, Hesperiidae, Zygaenidae)

Graellsia, 2003
La información corológica (datos de bibliografía, colecciones e inéditos) sobre las 143 especies de mariposas (Superfamilia Papilionoidea, y Familias Hesperiidae y Zygaenidae) de Portugal continental se ha reunido en una base de datos.
P. Garcia-Pereira, Enrique García-Barros, M. Munguira   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source