Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Letter to the Editor in Response to: Eagle SR, Henry RJ. Applying Dynamical Systems Theory to Improve Personalized Medicine Following Mild Traumatic Brain Injury. <i>Neurotrauma Rep</i> 2024 Jul 16;5(1):671-679; Doi: 10.1089/Neur.2024.0040. [PDF]
McGlennon TW.
europepmc +1 more source
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han +10 more
wiley +1 more source
Supplementary winter feeding is associated with higher recruitment rates in a population of a scavenging bird of prey. [PDF]
Nebel C, Penttinen I, Laaksonen T.
europepmc +1 more source
Thinking headteachers, thinking schools : how three headteachers are leading their schools towards becoming communities of enquiry [PDF]
Eagle, Sue +2 more
core
Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay +3 more
wiley +1 more source
Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking. [PDF]
Eagle AL +13 more
europepmc +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
The correlation between the styloid process length, angle, head shape, and eagle syndrome based on high-resolution CT three-dimensional reconstruction: a retrospective study. [PDF]
Duan J +6 more
europepmc +1 more source
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang +12 more
wiley +1 more source

