Results 41 to 50 of about 171,863 (295)

Does the order of invasive species removal matter? The case of the eagle and the pig. [PDF]

open access: yesPLoS ONE, 2009
BackgroundInvasive species are recognized as a primary driver of native species endangerment and their removal is often a key component of a conservation strategy.
Paul W Collins   +2 more
doaj   +1 more source

Aspects of Movement Ecology and Habitat Use of Migratory Raptors Using Satellite Telemetry from India to Central Asia

open access: yesBirds
Single individuals of the Greater Spotted Eagle (Clanga clanga), Indian Spotted Eagle (Clanga hastata), Tawny Eagle (Aquila rapax), Western Marsh Harrier (Circus aeruginosus), and two Pallid Harriers (Circus macrourus) were deployed with satellite ...
Mohan Ram   +9 more
doaj   +1 more source

Excessive lead burden among golden eagles in the Swiss Alps

open access: yesEnvironmental Research Letters, 2015
Fragments from lead ammunition pose a poisoning risk for predators like golden eagles that scavenge on non-retrieved carcasses or offal left behind by hunters. Three golden eagles were found in the Swiss Alps with an acute lead poisoning.
Milena M Madry   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell

open access: yesFunction, 2022
Defects in the pancreatic β-cell’s secretion system are well-described in type 2 diabetes (T2D) and include impaired proinsulin processing and a deficit in mature insulin-containing secretory granules; however, the cellular mechanisms underlying these ...
Kristen E Rohli   +9 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Population impact to bald eagles by ingested lead in New York State, 1990–2018

open access: yesWildlife Society Bulletin, 2023
While the recent population recovery of bald eagles (Haliaeetus leucocephalus) in New York State, USA, is a conservation success, evidence from necropsies suggest that ingested lead (Pb) from ammunition fragments is causing morbidity and mortality to ...
Brenda J. Hanley   +5 more
doaj   +1 more source

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