Results 81 to 90 of about 46,278 (259)

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

Developmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee, Ebenezer N. Yamoah, Jennifer Kersigo, Karen Elliott, Niya LaRoda, Gabriela Pavlinkova, Bernd Fritzsch   +6 more
wiley   +1 more source

Free Nasal Septal Cartilage Graft for Extensive Defects of the External Auditory Canal: A Case Report

Journal of Plastic and Reconstructive Surgery
External canal reconstruction of extensive tissue defects, including auricle or ear canal defects, is challenging. We describe the case of a 28-year-old man who underwent staged skin and nasal septum cartilage grafting for ear canal reconstruction after ...
Toru Miyanaga, Yuko Kinoshita, Takayoshi Kaneko, Mikio Yagishita, Miyuki Kishibe, Masanobu Yamashita, Kenichi Shimada   +6 more
doaj  

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

Exploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma, Hai‐Peng Wang, Yu‐Meng Jiang, Ke Lai, Ming‐Xian Li, Zhen Zhang, Li‐Na Gong, Jing‐Wei Lai, Kai‐Ming Su, Lu‐Yang Wang, Hui Wang, Shan‐Kai Yin, Hao He, Hai‐Bo Shi   +13 more
wiley   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

Investigating the Effect of Ear Canal Length on Improving Earplugs and Earmuffs Performance at 400 and 500 Hz Frequencies

International Journal of Environmental Health Engineering
Aim: The aim of this study was noise reduction at 400 Hz and 500 Hz frequencies using earplugs and earmuffs, by varying the length of a simulated ear canal.
Hossein Ebrahimi, Farhad Forouharmajd, Siamak Pourabdian, Kamyar Nazaryan   +3 more
doaj   +1 more source

Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann, Roman Ackermann, Klaus Jahn, John‐Martin Hempel   +3 more
wiley   +1 more source

Singing in the Ear Canal

The Iowa Review, 2005
I faint at my first everything in medical school. First cadaver. First surgery. First autopsy. Well not everything, not the first lecture. I even blow the tour, the first day. The tour's really a test. We're in, mcat scores high enough, first semester tuition paid. Our entire freshman class files into the sub basement, bound together tight as a brownie
openaire   +1 more source

Fluorescence‐Guided Detection of Perineural and Bony Invasion With Margin Correlation in Gingival Squamous Cell Carcinoma Using Panitumumab‐IRDye800

Head &Neck, EarlyView.
ABSTRACT Background Near‐infrared (NIR) fluorescence‐guided surgery using EGFR‐targeted tracers (e.g., panitumumab‐IRDye800CW) can provide real‐time visualization of tumors and margins in Head and Neck Squamous Cell Carcinoma. Prior studies have demonstrated its safety and potential to improve intraoperative decision‐making and margin assessment ...
Makenna Brown, Mabrooka Kazi, Hidenori Tanaka, Brandee Brown, Mitra Mehrad, Sarah Rohde, Eben Rosenthal, Kyle Mannion   +7 more
wiley   +1 more source

The Role of Multicancer Early Detection Tests in Head and Neck Squamous Cell Carcinoma: A Case Series

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) lacks an established screening program, and most cases are diagnosed at advanced stages. Multi‐cancer early detection (MCED) blood‐based assays represent a promising approach, yet real‐world clinical experience with MCED‐identified HNSCC remains limited.
Abhinav Talwar, Olivia Ben‐Levy, Nikhil Sriram, Sandeep Samant   +3 more
wiley   +1 more source