Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen +10 more
wiley +1 more source
Biologics: The Good, the Bad and the Future of Ear, Nose and Throat. [PDF]
Vincent V.
europepmc +1 more source
Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su +8 more
wiley +1 more source
Antibiogram Profiling of Antibiotics in Ear, Nose, and Throat Infections in Tertiary Healthcare Settings. [PDF]
Mariah Benedict Raj P +2 more
europepmc +1 more source
ABSTRACT Background Accurate pretreatment assessment of the extent of tumor invasion and status of cervical lymph node metastasis is essential for staging and treatment planning in HNSCC. Deep learning (DL) shows promise but is limited by methodological heterogeneity. Methods We conducted a systematic review and network meta‐analysis (PRISMA). Studies (
Jannik Ketschau +10 more
wiley +1 more source
Dexmedetomidine Nasal Spray on Emergence Agitation After Ear, Nose, and Throat Surgery: Protocol for a Randomized, Double-Blind, Controlled Trial. [PDF]
Wang D +6 more
europepmc +1 more source
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan +17 more
wiley +1 more source
Speech and language therapist-led clinics for low-risk suspected head and neck cancer referrals: A qualitative study of ear, nose and throat surgeons' views. [PDF]
Occomore-Kent LC +5 more
europepmc +1 more source
ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance +10 more
wiley +1 more source
Prospective Drug Utilization Evaluation Analysis in Outpatient Departments with Ear, Nose, and Throat Outpatients: Incorporating Benchmarks and World Health Organization Indicators. [PDF]
Mugada V +4 more
europepmc +1 more source

