Results 51 to 60 of about 5,927 (293)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Characterizing bone density pattern and porosity in the human ossicular chain using synchrotron microtomography

Scientific Reports
The auditory ossicles amplify and transmit sound from the environment to the inner ear. The distribution of bone mineral density is crucial for the proper functioning of sound transmission as the ossicles are suspended in an air-filled chamber.
Aleksandra Ivanovic, Fabian Schalbetter, Margaux Schmeltz, Wilhelm Wimmer, Marco Caversaccio, Marco Stampanoni, Anne Bonnin, Lukas Anschuetz   +7 more
doaj   +1 more source

Fiber-Based Laser Doppler Vibrometer for Middle Ear Diagnostics

Photonics
Laser Doppler vibrometry (LDV) is an essential tool in assessing by evaluating ossicle vibrations. It is used in fundamental research to understand hearing physiology better and develop new surgical techniques and implants.
Adam T. Waz, Marcin Masalski, Krzysztof Morawski   +2 more
doaj   +1 more source

Human otopathology in scleroderma

Laryngoscope Investigative Otolaryngology, 2023
Objective Scleroderma is a complex chronic progressive immune‐mediated disease that causes fibrosis of the skin and internal organs, and vasculopathy. Ear involvement has been poorly studied in patients with scleroderma.
Melissa Castillo‐Bustamante, Prithwijit Roychowdhury, Dhrumi Gandhi, Elliott D. Kozin, Aaron K. Remenschneider   +4 more
doaj   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam, Yong Kwon Chae, Seoung‐Jin Hong, Younggen Lee, Dongwook Yang, Byunggi Kim, Sang Wook Kang, Young‐Jin Kim   +7 more
wiley   +1 more source

Automated segmentation of the middle ear ossicles and tympanic cavity based on a deep-learning model

Informatics in Medicine Unlocked
Background: Prior to middle ear surgery, it is desirable to get concise information about the anatomy of the middle ear ossicles and the tympanic cavity in order to analyze the topographical conditions and identify anatomical impairments.
Christopher Späth, Christian Schwarzbauer, Florian Schrötzlmair   +2 more
doaj   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source

Study of the effect of friction between the ossicles of the middle ear [PDF]

, 2007
The human ear is a complex biomechanical system and is divided by three parts: outer, middle and inner ear. The middle ear is formed by three ossicles (malleus, incus and stapes), ligaments, muscles and tendons, that amplify the sound, sending the sound
Almeida, Eurico de, Mendes Ferreira, António J., Gentil, Fernanda, Natal Jorge, Renato M., Moreira, Miguel   +4 more
core   +1 more source

Prognostic Impact of Tumor Extension in Patients With Advanced Temporal Bone Squamous Cell Carcinoma

Frontiers in Oncology, 2020
Objective: The extreme rarity of temporal bone squamous cell carcinoma (TB-SCC) has delayed the accumulation of high-quality clinical evidence. Our objective here was to explore anatomical factors associated with the prognosis of T4 TB-SCC cases.Study ...
Noritaka Komune, Masaru Miyazaki, Kuniaki Sato, Koji Sagiyama, Akio Hiwatashi, Takahiro Hongo, Kensuke Koike, Teppei Noda, Ryutaro Uchi, Ryunosuke Kogo, Nana Akagi Tsuchihashi, Shogo Masuda, Takashi Nakagawa   +12 more
doaj   +1 more source