Results 61 to 70 of about 10,287 (254)

Characterizing bone density pattern and porosity in the human ossicular chain using synchrotron microtomography

Scientific Reports
The auditory ossicles amplify and transmit sound from the environment to the inner ear. The distribution of bone mineral density is crucial for the proper functioning of sound transmission as the ossicles are suspended in an air-filled chamber.
Aleksandra Ivanovic, Fabian Schalbetter, Margaux Schmeltz, Wilhelm Wimmer, Marco Caversaccio, Marco Stampanoni, Anne Bonnin, Lukas Anschuetz   +7 more
doaj   +1 more source

Fiber-Based Laser Doppler Vibrometer for Middle Ear Diagnostics

Photonics
Laser Doppler vibrometry (LDV) is an essential tool in assessing by evaluating ossicle vibrations. It is used in fundamental research to understand hearing physiology better and develop new surgical techniques and implants.
Adam T. Waz, Marcin Masalski, Krzysztof Morawski   +2 more
doaj   +1 more source

A Comprehensive Three-Dimensional Model of the Cochlea [PDF]

, 2003
The human cochlea is a remarkable device, able to discern extremely small amplitude sound pressure waves, and discriminate between very close frequencies.
Allaire, Allen, Allen, Beyer, Bogert, Chadwick, Clark, de Boer, Edward Givelberg, Fletcher, Geisler, Gold, Holmes, Inselberg, Johnstone, Julian Bunn, Kemp, Khanna, Kim, Kohllöffel, Kolston, Kolston, Lesser, Leveque, Loh, Manoussaki, Nuttall, Parthasarati, Peskin, Peskin, Peskin, Peterson, Ramamoorthy, Ranke, Rhode, Robles, Schroeder, Sellick, Siebert, Steele, Steele, Steele, Viergever, von Békésy, Zweig, Zwislocki, Zwislocki   +46 more
core   +2 more sources

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Human otopathology in scleroderma

Laryngoscope Investigative Otolaryngology, 2023
Objective Scleroderma is a complex chronic progressive immune‐mediated disease that causes fibrosis of the skin and internal organs, and vasculopathy. Ear involvement has been poorly studied in patients with scleroderma.
Melissa Castillo‐Bustamante, Prithwijit Roychowdhury, Dhrumi Gandhi, Elliott D. Kozin, Aaron K. Remenschneider   +4 more
doaj   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam, Yong Kwon Chae, Seoung‐Jin Hong, Younggen Lee, Dongwook Yang, Byunggi Kim, Sang Wook Kang, Young‐Jin Kim   +7 more
wiley   +1 more source

Automated segmentation of the middle ear ossicles and tympanic cavity based on a deep-learning model

Informatics in Medicine Unlocked
Background: Prior to middle ear surgery, it is desirable to get concise information about the anatomy of the middle ear ossicles and the tympanic cavity in order to analyze the topographical conditions and identify anatomical impairments.
Christopher Späth, Christian Schwarzbauer, Florian Schrötzlmair   +2 more
doaj   +1 more source

Evaluation of 4 Outcomes Measures in Microtia Treatment: Exposures, Infections, Aesthetics, and Psychosocial Ramifications. [PDF]

, 2017
BackgroundIn craniofacial microsomia, microtia and canal atresia pose formidable reconstructive challenges. We review our institutional experience in treating microtia and atresia to identify variables associated with 4 outcomes measures: complications ...
Bradley, James P, Dubina, Emily, Ishiyama, Akira, Lee, Justine C, Mandelbaum, Rachel S, Martins, Deborah B, Park, Sarah H, Volpicelli, Elizabeth J   +7 more
core  

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source