Results 101 to 110 of about 109,515 (359)
Advanced Science, EarlyView.Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
Noninvasive in vivo optical detection of biofilm in the human middle ear [PDF]
, 2012 Cac T. Nguyen +6 more
openalex +1 more source
Advanced Science, EarlyView.Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka +3 more
wiley +1 more source
Analysis of high load dampers [PDF]
High load damping requirements for modern jet engines are discussed. The design of damping systems which could satisfy these requirements is also discusseed. In order to evaluate high load damping requirements, engines in three major classes were studied;
Bhat, S. T., Buono, D. F., Hibner, D. H.
core +1 more source
Socially Relevant Practice in Art, Culture, and Environment [PDF]
, 1983 What is socially relevant practice? From my perspective, socially relevant practice has to do with making knowledge available to students that enables them to know about social institutions and contexts associated with the visual arts.
Johnson, Nancy R.
core +1 more source
Retracted: Clinical Analysis of Ear Congestion after Balloon Eustachian Tuboplasty (BET) with or without Tympanostomy Tube Insertion [PDF]
, 2023 Evidence-Based Complementary and Alternative Medicine
openalex +1 more source
Advanced Science, EarlyView.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
A Lexicographer\u27s Search [PDF]
, 1983 When I was researching my about-to-be-published A Glossary of Colonial American Words (Lederer\u27s Lexicon) I encountered only a handful for which I could not find definitions in the many sources available.
Lederer, Richard M., Jr.
core +1 more source
Advanced Science, EarlyView.This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou +7 more
wiley +1 more source
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source