On the association between earlobe crease and the carotid intima-media thickness: A population-based study [PDF]
Heliyon, 2019 The earlobe crease (ELC) has been linked to coronary artery disease, but there is limited information on the association between ELC and extracranial atherosclerosis.
Oscar H. Del Brutto +4 more
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Diagonal Earlobe Crease and the Risk of New-Onset Atrial Fibrillation After Cavotricuspid Isthmus Ablation in Patients with Typical Atrial Flutter [PDF]
LifeBackground: Atrial fibrillation (AF) frequently develops in patients with atrial flutter (AFL), even after successful cavotricuspid isthmus (CTI) ablation. Identifying simple clinical markers for early detection is crucial. Diagonal earlobe crease (ELC),
Moo-Nyun Jin, Young Ju Kim, Changho Song
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The Association between Earlobe Crease (Frank’s Sign) and Abnormal Ankle-Brachial Index Determination Is Related to Age: A Population-Based Study [PDF]
International Journal of Vascular Medicine, 2018 Background. Information on the association between earlobe crease (ELC) and peripheral artery disease is limited. We assessed this association in community-dwelling older adults. Study Design.
Oscar H. Del Brutto +4 more
doaj +2 more sources
Patients With Earlobe Crease May Associate With Lower Concentration of the Age-Suppressing Hormone Klotho [PDF]
International Journal of General Medicine, 2021 Wei-Wei Chen
exaly +2 more sources
Diagonal Earlobe Crease (Frank’s Sign) for Diagnosis of Coronary Artery Disease: A Systematic Review of Diagnostic Test Accuracy Studies [PDF]
Journal of Clinical Medicine, 2021 Andrzej Surdacki +2 more
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Diagnostic model for angiographic obstructive coronary artery disease combining CHG, DELC, and traditional risk factors: a bootstrap validation study [PDF]
Frontiers in EndocrinologyObjectiveTo construct and internally validate a diagnostic model for angiographic obstructive coronary artery disease (obstructive CAD) (defined as ≥50% stenosis on coronary angiography) incorporating the cholesterol, high-density lipoprotein, and ...
Wenxin Lin +8 more
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World Neurosurgery: XObjective: To evaluate the association of diagonal earlobe crease (DELC, Frank's sign), laterality, and type of DELC with the presence of intracranial arterial aneurysms (IAA).
Bayron A Sandoval-Bonilla +2 more
exaly +3 more sources
Warning Function of Frank’s Sign in Pre-Existing Cardiac Disease Patients: A Case Report [PDF]
Case Reports in CardiologyFrank’s sign (FS) refers to a diagonal skin fold between the tragus and the outer edge of the earlobe. FS has been identified as an independent variable in coronary artery disease (CAD). Young patients with FS and previous myocardial infarction are still
Mingzhe Wang +7 more
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Relationship between diagonal earlobe crease (Frank’s sign) and international index of erectile dysfunction score (IIEF-5) [PDF]
Journal of Men's Health, 2023 The objective of this study is to examine the association between erectile dysfunction (ED) and the presence of diagonal earlobe crease (DELC), a physical sign commonly associated with atherosclerosis.
Ugur Taylan Bilgilisoy
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Correction: Predictive value of atherogenic index of plasma in combination with diagonal earlobe crease in coronary heart disease [PDF]
Frontiers in Cardiovascular MedicineRuoling Guo +8 more
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