Results 71 to 80 of about 6,996,939 (272)
RAISE Special Interest Groups (Early Career Researchers and Research & Evaluation) Collaboration: A Case Study [PDF]
In the academic year 2022/23, the RAISE Special Interest Groups for Early Career Researchers and Research & Evaluation collaboratively developed a professional development programme for HE colleagues new to writing about student engagement.
Wilko Luebsen +3 more
core +4 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Reflections on mentorship as an early career researcher
It is my great honor to receive the 2022 Günter Blobel Early Career Award from the American Society for Cell Biology. Reflecting upon my research and career trajectory, I recognize the incredible support of my mentors and the hard work of everyone within my lab.
openaire +2 more sources
Twin Ports Early-Career Researchers Fall Forum & Workshop (2019-10-29)
October 29|2019; University of Minnesota - Duluth; Library Rotunda; +Workshop|Networking for scientists (10:30-12:30); +Career Panel Discussion|Applying, interviewing, & negotiating (1:30-3:30); +Keynote|Science as a business and mapping your career (3 ...
Twin Ports Early-Career Researchers
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Peer review is being criticized for its sluggishness and review quality. Swiftly identifying available reviewers and cultivating a pool of specialized experts is crucial to avoid delays and ensure a seamless peer review process.
Amit Kumar, Manjunath P. Puranik
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Text recycling and dissertation overlap in the era of open access [PDF]
As doctoral theses become increasingly accessible through open repositories and similarity-checking software is applied more widely, many early-career researchers encounter the rejection of manuscripts that are legitimately derived from their theses ...
Olivier Pourret
doaj +3 more sources
Navigating Open Research - A Guide for Early Career Researchers [PDF]
Welcome to Navigating Open Research – A Guide for Early Career Researchers. This guide is designed to help you at each stage of your research journey. From preparing your research project and discovering relevant resources (Section 1) to research data management and reproducibility (Section 2), writing and publishing (Section 3), sharing and publishing
Aoife Coffey +11 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

