Results 51 to 60 of about 704,542 (298)
Sensitivity Cost-Benefit Analysis to Support Knowledge Capture of Industrial Interests [PDF]
, 2009 Organised by: Cranfield UniversityIn strategic industrial fields, emerging technologies are evolving into strategic enabling technologies for next generation products and services (IPS2).
Paci, A. M., Chiacchio, M. S.
core
JCO Global Oncology, 2021 Diagnosing cancer earlier can enable timely treatment and optimize outcomes. Worldwide, national cancer control plans increasingly encompass early diagnosis programs for symptomatic patients, commonly comprising awareness campaigns to encourage prompt ...
Minjoung Monica Koo +9 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Impact Assessment in the EU: The State of the Art and the Art of the State. CEPS Paperbacks. January 2006 [PDF]
, 2006 Policy-makers increasingly see impact assessment as the philosopher’s stone that will enhance the quality of EU legislation in the years to come, leading Europe back onto the Lisbon track.
Renda, Andrea
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Structured approaches to benefit-risk assessment: a case study and the patient perspective [PDF]
, 2014 Assessing the utility of structured approaches to benefit-risk assessment of medicinal products is challenging, in part due to the lack of a gold standard for results and the uncertainty inherent in the data.
Levitan, Bennett +2 more
core +1 more source
AI-enabled routine H&E image based prognostic marker for early-stage luminal breast cancer
npj Precision Oncology, 2023 Breast cancer (BC) grade is a well-established subjective prognostic indicator of tumour aggressiveness. Tumour heterogeneity and subjective assessment result in high degree of variability among observers in BC grading.
Noorul Wahab +16 more
doaj +1 more source
Sensors, 2022 Early identification of infants at risk of neurodevelopmental delay is an essential public health aim. Such a diagnosis allows early interventions for infants that maximally take advantage of the neural plasticity in the developing brain.
Marcelo Aguilar-Rivera +9 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source