Results 71 to 80 of about 704,542 (298)

Assessment and testing. [PDF]

, 2000
In this brief article, I discuss the relationship between language testing and the other sub-disciplines of applied linguistics and also the relationship, as I see it, between testing and assessment.
Caroline Clapham, Clapham, Caroline
core  

Conditional Resolutions in the Amnog Early Benefit Assessment [PDF]

Value in Health, 2014
Assmann, G., Schmidt, U., Drechsler, M., Pfannkuche, M.   +3 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Preoperative assessment and prognostic prediction of gastric cancer patients with peritoneal metastasis using 18F-FDG PET/CT before conversion surgery

EJNMMI Research
Background Conversion therapy followed by conversion surgery (CS) can improve the prognosis of gastric cancer (GC) patients with peritoneal metastasis (PM). However, patients benefit differently.
Yao Peng, Min Shi, Daxi Xiong, Sheng Lu, Ying Miao, Hong Yuan, Chao Yan, Zhenggang Zhu, Biao Li, Zhongyin Yang, Jiajia Hu   +10 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The early clinical features of dengue in adults: challenges for early clinical diagnosis. [PDF]

, 2011
BACKGROUND: The emergence of dengue throughout the tropical world is affecting an increasing proportion of adult cases. The clinical features of dengue in different age groups have not been well examined, especially in the context of early clinical ...
Chaterji, S., Lee-Ching Ng, Martin L. Hibberd, Chow, Angelia, Sharon W. S. Tan, Chua, C.R., Vasudevan Subhash G., Martin L Hibberd, Ooi Eng Eong, Leo Yee Sin, Choon Rong Chua, Chua Robert, Vasudevan, Subhash G, Chaterji, Shera, Leo, Yee Sin, Cheung, Yin Bun, Ng, Lee-Ching, Leo, Y.S., Chow, A., Ong Adrian, Cheung Yin Bun, Lim Wen Yan, Yin Bun Cheung, Chua Choon Rong, Adrian Ong, Yee Sin Leo, Low, Jenny GH, Hibberd, M.L., Subhash G Vasudevan, Low Jenny G. H., Ong, A., Cheung, Y.B., Ooi, E.E., Ng, L.-C., Low, J.G.H., Vasudevan, S.G., Jenny G. H. Low, Hibberd Martin L., Wen Yan Lim, Eng Eong Ooi, Tan Li Kiang, Lee, K.W., Jenny G H Low, Ong, Adrian, Lim, W.Y., Shera Chaterji, Chua, R., Koon Wui Lee, Tan Sharon W. S., Lim, Wen Yan, Ng Lee-Ching, Subhash G. Vasudevan, Lee Koon Wui, Robert Chua, Chaterji Shera, Ooi, Eng Eong, Hibberd, Martin L, Tan, L.K., Tan, S.W.S., Angelia Chow, Li Kiang Tan, Lee, Koon Wui, Tan, Sharon WS, Tan, Li Kiang, Sharon W S Tan, Chua, Choon Rong, Chua, Robert, Chow Angelia   +67 more
core   +1 more source

Chemotherapy in older patients with early breast cancer

Breast
The incidence of breast cancer increases with age. Particularly in ageing societies, breast cancer has a significant impact on both the older patient and the healthcare system.
Marcus Schmidt, Sibylle Loibl
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source