Results 141 to 150 of about 1,633,412 (393)

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma   +14 more
wiley   +1 more source

The impact of lockdown on child adjustment: a propensity score matched analysis

open access: yesBMC Psychology
The COVID-19 pandemic has had an inestimable impact worldwide, challenging the daily lives and interactions of children and their families. In 2022, Shanghai implemented a three-month lockdown in response to an acceleration of positive cases during the ...
Wanjuan Weng   +7 more
doaj   +1 more source

Education and Economic Mobility [PDF]

open access: yes, 2008
Surveys the literature on how education affects intergenerational mobility. Discusses the impacts of parents' education, financial resources, GED and job training programs, K-12 quality improvements, and early childhood education and ...
Nathan Grawe
core  

Low pay but still we stay: Retention in early childhood education and care

open access: yesJournal of Industrial Relations, 2018
A professional, skilled and engaged early childhood workforce is critical to economic and social productivity and positive life trajectories for children.
Paula McDonald, K. Thorpe, S. Irvine
semanticscholar   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

open access: yesAdvanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich   +8 more
wiley   +1 more source

early childhood education.

open access: yes
ABSTRACT The purpose of this study is to make assessment the Early childhood education. The overall aim of this study was guided by the very important objectives: To defines the impact of job enrichment on employee retention to the business in some selected businesses in Mogadishu, Somalia. The study was conducted from January 2024 to June 2024.
openaire   +2 more sources

Guidelines for Selecting Professional Development for Early Childhood Teachers [PDF]

open access: yes, 2019
Engaging teachers of young children in effective in-service professional development is a critical component of establishing high quality early childhood education.
Gerde, Hope K.   +2 more
core   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim   +12 more
wiley   +1 more source

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