Results 141 to 150 of about 1,193,465 (362)
Manajemen Pendidikan Paud Al- Fath Sabang [PDF]
, 2012 Early childhood education today has become the need of society. Although early childhood education, including education level of recognition, but education has contributed a lot to the development of children's education. This study aims to determine the
Bustami, B. (Bustami) +2 more
core
The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation
Advanced Science, EarlyView.ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang +16 more
wiley +1 more source
Child care and early childhood education in Australia [PDF]
Presents information about the types of child care used by children in Australia, highlighting how arrangements change as children grow, and how they vary for families of different characteristics. Summary Child care and early childhood education hold a
Jennifer Baxter
core
Advanced Science, EarlyView.This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan +11 more
wiley +1 more source
Advanced Science, EarlyView.PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li +6 more
wiley +1 more source
Collaborative relationships in practice: Possibilities and challenges [PDF]
, 2006 The following three papers examine what collaboration is happening in New Zealand’s early childhood education services currently, and provide exemplars of collaboration in three key areas: with parents and whänau; with Mäori, iwi and marae; and with ...
Mitchell, Linda
core +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
Advanced Science, EarlyView.The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Early Childhood Experiences: Laying the Foundation for Health Across a Lifetime [PDF]
, 2008 Outlines current research on how factors such as parents' education, income, and race/ethnicity affect children's development and health throughout life, as well as how early childhood development programs can mitigate socioeconomic ...
Paula Braveman +2 more
core
Advanced Science, EarlyView.Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao +16 more
wiley +1 more source