Results 151 to 160 of about 12,626,452 (304)
Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis
Advanced Science, EarlyView.Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
ABSTRACT The purpose of this study is to make assessment the Early childhood education. The overall aim of this study was guided by the very important objectives: To defines the impact of job enrichment on employee retention to the business in some selected businesses in Mogadishu, Somalia. The study was conducted from January 2024 to June 2024.
openaire +2 more sources
Investigating early childhood education for sustainability : insights from history and literature
, 2013 Seemingly straightforward tasks often have a way of becoming complex. This was the case for our guest editorial team charged with creating Early Childhood Australia’s Best of Sustainability publication drawn from the the Australasian Journal of Early ...
Davis, Julie M. +2 more
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Interfacial Redox Engineering Driven Forming‐Free Intrinsic Bipolar Switching in SiOx Memristors
Advanced Electronic Materials, EarlyView.Redox engineering at the Sc/SiOx interface spontaneously establishes a stable oxygen‐vacancy‐rich region that preconditions the defect landscape in SiOx memristors. This facilitates controlled vacancy percolation, eliminates electroforming, and enables forming‐free bipolar resistive switching with improved switching uniformity, long endurance, and ...
Biswajit Jana +3 more
wiley +1 more source
An Aotearoa New Zealand perspective on inclusive early childhood education
, 2019 Children are acknowledged as precious taonga/treasure in Aotearoa New Zealand’s national early childhood curriculum and its founding Māori principles.
Li,, AM-C +3 more
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Extreme Weather Events and Consumer Food Responses
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT This study investigates consumer food responses to Hurricanes Helene and Milton, which affected a swath of the Southeastern U.S. in 2024. Using representative consumer survey data from six affected states, we analyze 10 distinct food responses classified into ex ante and ex post responses, and examine their associations with food insufficiency
Ahmad Zia Wahdat, Joseph Balagtas
wiley +1 more source
Chinese Trade Competition and Rural Mexican Migration
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT China's accession to the World Trade Organization in 2001 reshaped global trade, reducing U.S. demand for Mexican manufactured goods and weakening Mexico's manufacturing employment. This study estimates how this trade‐induced decline affected migration and employment decisions among rural Mexicans.
Zachariah Rutledge, Joaquin Mayorga
wiley +1 more source