Results 151 to 160 of about 13,229,627 (267)

The ‘state of play’ in Australia: Early childhood educators and play-based learning

open access: yes, 2014
This article provides an overview of the Education Meets Play study that will investigate early childhood educators’ use of play-based learning, now mandatory under the National Quality Standard.
Shield, Paul   +3 more
core  

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

Implementing co-teaching in pre-primary education : A Finnish multiple case study

open access: yes
This study examined co-teaching between early childhood special education teachers (ECSETs) and early childhood education teachers (ECTs) in two Finnish pre-primary education groups, aiming to understand how ECSETs and ECTs can implement co-teaching as a
Ström, Kristina   +5 more
core   +1 more source

LLMs as Representation Generators for Gradient‐Free Scientific Optimization: A Case Study in Battery Fast Charging

open access: yesAdvanced Science, EarlyView.
Large language models serve as representation generators for gradient‐free scientific optimization. Two complementary approaches produce executable battery‐charging policies either directly or through LLM‐designed neural representations coupled to Bayesian optimization.
Ge Lei   +3 more
wiley   +1 more source

Yesterday, Today, Tomorrow: Globalization and Early Childhood Education in Hong Kong

open access: yes, 2006
In the midst of educational reforms that are aimed at increasing the competitiveness of Hong Kong Special Administrative Region (HKSAR) in a globalized economy, early childhood education in Hong Kong retains unique ties to the colonial past and maintains
Grieshaber, Susan J.
core  

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

open access: yesAdvanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen   +4 more
wiley   +1 more source

Minutes, College of Education Early Childhood Education Committee Meeting, April 24, 2008

open access: yes, 2007
Minutes from the April 24, 2008, meeting of the Early Childhood Education Committee of the University of South Florida St.
University of South Florida St. Petersburg. College of Education. Early Childhood Education Committee.   +1 more
core  

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