Results 251 to 260 of about 1,784,584 (391)

Use Of Augmented Reality As A Learning Media In Early Childhood Education Solideo Perumnas I Jayapura

, 2020
Remuz MB Kmurawak, Diana Setyaningsih
openalex   +2 more sources

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Health Education in the Curriculum of Early Childhood Education in Galicia, Spain: An Analysis of Decree 150/2022. [PDF]

Healthcare (Basel)
Gigirey-Vilar A, Navarro-Patón R, Martínez-Isasi S, Rodríguez-Fernández JE.   +3 more
europepmc   +1 more source

Quality Of Colombian Early Childhood Education: An Exploratory Study Of Teacher-Child Interactions

, 2019
Elsa Lucia Escalante‐Barrios, İbrahim H. Acar, Sonia Suárez, Helen H. Raikes   +3 more
openalex   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

COVID-19 School Disruptions in Early Childhood Education and Children's Early Elementary School Outcomes: Findings from the Smart Beginnings Randomized Clinical Trial. [PDF]

Early Child Dev Care
Miller EB, Canfield CF, Aviles AI, Hunter LJ, Shaw DS, Mendelsohn AL, Morris-Perez PA.   +6 more
europepmc   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source

Evaluating the Sustaining Play, Sustaining Health programme in Australian early childhood education and care services: a pilot randomized controlled trial. [PDF]

Health Promot Int
Imad N, Hall A, Giles L, Pearson N, Shoesmith A, Nathan N, Grady A, Renda A, Belski R, Yoong S.   +9 more
europepmc   +1 more source

ENHANCING FINANCING MECHANISMS FOR EARLY CHILDHOOD AND SCHOOL EDUCATION FACILITIES: INTERNATIONAL LESSONS FOR UZBEKISTAN

Murodbek Boltaboev
openalex   +1 more source