Results 271 to 280 of about 1,784,584 (391)

Evaluating the scale-up of the Play Active programme for children's physical activity in early childhood education and care services: a national type III hybrid effectiveness-implementation trial protocol. [PDF]

BMJ Open
Christian H, Maher C, Trost SG, Schipperijn J, Murray K, Li I, Nathan A, Papageorgiou A, Mclaughlin M, Bauman A.   +9 more
europepmc   +1 more source

Briefing Paper: Men in Early Childhood Education

, 2009
Julie A. Jones
openalex   +2 more sources

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Early childhood education and handgun carrying, serious fighting, and assault charges: a retrospective cohort study. [PDF]

Health Aff Sch
Schleimer JP, Hajat A, Joseph G, Rivara F, Sun M, Rowhani-Rahbar A.   +5 more
europepmc   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Tiny Bites, a digital health intervention delivered in early childhood education and care centres to support educators and caregivers to prevent childhood obesity: study protocol for a cluster randomised controlled trial. [PDF]

BMJ Open
Yoong SL, Lum M, Leung GKW, Pearson N, Truby H, Dix C, Moumin NA, Wolfenden L, Ananthapavan J, Grady A, Wiggers J, Delaney T, Rychetnik L, Romiti M, Lamont H, Stanley S, Lim M, Oldmeadow C, Mastersson N, Sutherland R.   +19 more
europepmc   +1 more source

A Basic Study for Utilizing Big Data in Early Childhood Education

, 2017
Yeon Seung Lee
openalex   +1 more source

Multisectoral Convergence of Food, Nutrition and Sanitation Programs for Child Health: Evidence From Country‐Level Programs in India

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper underscores the critical role of multisectoral convergence in enhancing child health, particularly in addressing anemia, a micronutrient deficiency linked to both diet and sanitation. We explore how the integration of nationwide food and nutrition programs with sanitation initiatives impacts anemia in Indian children under three ...
Soumya Gupta, Payal Seth, Prabhu Pingali
wiley   +1 more source

On summoning queer joy in early childhood education: Some findings from New Brunswick, Canada. [PDF]

J Early Child Res
Burkholder C, Whitty P, Malins P, Keehn M.   +3 more
europepmc   +1 more source

Analysis on the Environments and Effectiveness of Early Childhood Education and Childcare Policies: Mainly in Finland, England and Japan

, 2017
장민영, 이진화, Eun Hye Park
openalex   +1 more source