Results 161 to 170 of about 9,208,125 (300)

Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration

, 2015
Pearse A Keane,1 Gabriella de Salvo,2 Dawn A Sim,1 Srini Goverdhan,2 Rupesh Agrawal,1 Adnan Tufail1 1NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, 2Department ...
Tufail A, Keane PA, de Salvo G, Goverdhan S, Sim DA, Agrawal R   +5 more
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SPOT: An Early Detection Tool for Predicting Pain Trajectories Following Intra-Articular Injections. [PDF]

J Orthop Res
Nelson BL, Jayaram P, Boden SD, Mautner K, Gottschalk MB, Myer GD, Drissi H, Diekfuss JA.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Early Hearing Detection and Intervention (EHDI) Program progress in action

More and more deaf and hard of hearing babies are being identified early.\u2022 In 2000 \u2013 855 babies identified as deaf or hard of hearing.\u2022 In 2005 \u2013 2634 babies identified as deaf or hard of hearing.\u2022 In 2014 \u2013 6163 babies ...

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Circulating methylated promoters of HK2 and EGFR as biomarkers in the early detection of cancer. [PDF]

Front Oncol
Jannu M, Ummanni R, Jinka R.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Training the Trainers: Building Capacity for Early Detection of First-Episode Psychosis in Primary Care. [PDF]

Early Interv Psychiatry
Noto C, Rosa FH, Vargas HO, Porcu M, Machado RCBR, Nunes SOV.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

National Breast and Cervical Cancer Early Detection Program through the years\u20131990 to today

On August 10, 1990, the United States Congress enacted the Breast and Cervical Cancer Mortality Prevention Act of 1990. The Act directed CDC to fund states for the purposes of screening women for breast and cervical cancer and referring them for ...

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