Results 111 to 120 of about 8,732,098 (315)
Giant cell arteritis: early diagnosis is key
, 2019 Iyza F Baig,1 Alexis R Pascoe,1 Ashwini Kini,2 Andrew G Lee2–9 1McGovern Medical School, The University of Texas Health Science Center in Houston, Houston, TX, USA; 2Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital ...
Pascoe AR, Lee AG, Baig IF, Kini A
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Early diagnosis of dementia by GPs: an exploratory study of attitudes
, 2000 The capacity of early diagnosis of dementia to facilitate effective treatment and care is well established. The pivotal role of the GP has also been identified by research, although accuracy in detecting and diagnosing dementia at an early stage varies ...
Mason, Jonathan +14 more
core +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Sustaining Early Success: Delaware’s Strategic Plan for a Comprehensive Early Childhood System
, 2013 2013 Annual Report and Strategic Plan of the Delaware Early Childhood ...
Delaware Early Childhood Council
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Oregon Early Childhood Inclusion indicators initiative annual report. Russian
, 2022 This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government ...
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
BMC CancerObjectives The 9th edition of the lung cancer tumor-node-metastasis (TNM) staging system downgrades certain non-small cell lung cancer (NSCLC) patients from stage IIIA (T1N2) to IIB(T1N2a).
Tong Wu +4 more
doaj +1 more source