Results 91 to 100 of about 8,732,098 (315)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundBrucellosis remains an important public health problem globally. Rapid and accurate diagnosis is crucial for the treatment of brucellosis. However, current diagnostic methods for brucellosis are limited, posing significant clinical challenges ...
Junwei Wu +55 more
doaj +1 more source
Green Processing and Synthesis, 2020 White-light emitting lanthanide(iii) metal-organic coordination polymers (LMOCPs) were prepared via a green synthesis method performed in pure aqueous solution at room temperature without using toxic solvent and reagents.
Zhang Yaoyao +7 more
doaj +1 more source
Early diagnosis of autism and impact on prognosis: a narrative review
, 2013 Elisabeth Fernell,1 Mats Anders Eriksson,1,2 Christopher Gillberg11Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 2Department of Women's and Children's Health, Karolinska Institute ...
Gillberg C, Fernell E, Eriksson MA
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Synthetic circRNA therapeutics: innovations, strategies, and future horizons
MedCommSmall molecule drugs are increasingly emerging as innovative and effective treatments for various diseases, with mRNA therapeutics being a notable representative.
Jingsheng Cai +9 more
doaj +1 more source
CAR-NK Cell Therapy: A Transformative Approach to Overcoming Oncological Challenges
BiomoleculesThe use of chimeric antigen receptor (CAR) in natural killer (NK) cells for cancer therapy is gaining momentum, marking a significant shift in cancer treatment.
Wangshu Li +4 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Parents’ responses to their child’s diagnosis of Autism Spectrum Disorder (ASD)
, 2010 Although a significant amount of research has reported the level of parental satisfaction with the disclosure of a diagnosis, little has documented their emotional responses after the diagnosis, their perceptions of the future, and the potential impact ...
Evans, Amber
core +1 more source
The Early Diagnosis of Rickets [PDF]
Archives of Disease in Childhood, 1949 J D, GRAY, F S, CARTER
openaire +2 more sources