Results 91 to 100 of about 2,379,974 (319)

Autism spectrum disorders [PDF]

, 2011
The earlier that children with an Autism Spectrum Disorder (ASD) receive referral, diagnosis and intervention, the better the long-term results are for those children and their families (Barbaro & Dissanyake, 2009; Wiggins et al., 2006; Mandell et al.
Centre for Community Child Health
core  

Adverse Perinatal and Early Life Outcomes following 15q11.2 CNV Diagnosis

, 2021
The copy number variation (CNV) of 15q11.2, an emerging and common condition observed during prenatal counseling, is encompassed by four highly conserved and non-imprinted genes—TUBGCP5, CYFIP1, NIPA1, and NIPA2—which are reportedly related to ...
Chien-Hong Lee, Jenn-Jeih Hsu, Steven W. Shaw, Tai-Ho Hung, Fu-Chieh Chu, Liang-Ming Lo   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Synthetic circRNA therapeutics: innovations, strategies, and future horizons

MedComm
Small molecule drugs are increasingly emerging as innovative and effective treatments for various diseases, with mRNA therapeutics being a notable representative.
Jingsheng Cai, Zonghao Qiu, William Chi‐Shing Cho, Zheng Liu, Shaoyi Chen, Haoran Li, Kezhong Chen, Yun Li, Chijian Zuo, Mantang Qiu   +9 more
doaj   +1 more source

Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis

Frontiers in Cellular and Infection Microbiology
BackgroundBrucellosis remains an important public health problem globally. Rapid and accurate diagnosis is crucial for the treatment of brucellosis. However, current diagnostic methods for brucellosis are limited, posing significant clinical challenges ...
Junwei Wu, Junwei Wu, Junwei Wu, Junwei Wu, Junwei Wu, Lei Zhang, Yingxin He, Yingxin He, Yingxin He, Yingxin He, Yingxin He, Haiyi Deng, Haiyi Deng, Haiyi Deng, Haiyi Deng, Haiyi Deng, Feiyang Cao, Feiyang Cao, Feiyang Cao, Feiyang Cao, Feiyang Cao, Yuheng Liu, Yuheng Liu, Yuheng Liu, Yuheng Liu, Yuheng Liu, Peiying Peng, Jin Su, Jin Su, Jin Su, Jin Su, Jin Su, Jie Wei, Xiaoye Lin, Qingxia Yi, Lei Zhan, Lei Zhan, Lei Zhan, Lei Zhan, Lei Zhan, Xiaomao Yin, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yao Liao, Yao Liao, Yao Liao, Yao Liao, Yao Liao, Lifu Wang, Lifu Wang, Lifu Wang, Lifu Wang, Lifu Wang   +55 more
doaj   +1 more source

THE DIAGNOSIS OF EARLY PHTHISIS. [PDF]

The Lancet, 1918
n ...
openaire   +2 more sources

Recommendations for diagnosis and treatment Early diagnosis of rheumatic diseases: an evaluation of the present situation and proposed changes

, 2015
Musculoskeletal pain is a very common complaint, affecting 30–40% of the European population. It is estimated that approximately 400,000 Poles suffer from inflammatory rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis and psoriatic
Brygida Kwiatkowska, Jerzy Gryglewicz, Filip Raciborski, Maria Maślińska, Anna Kłak   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Early Diagnosis of Measles [PDF]

The American Journal of the Medical Sciences, 1915
n ...
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source