Results 91 to 100 of about 1,564,555 (265)

Early Failure of Locking Compression Plates in Pediatric Proximal Femoral Fracture. [PDF]

J Pediatr Soc North Am, 2023
Cope SR, Wideman M, Sheffer BW, Sawyer JR, Beaty JH, Warner WC, Spence DD, Kelly DM.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Design of an intelligent failure diagnosis and early warning system for tunnel drilling rigs in coal mines

Meitian dizhi yu kantan
ObjectiveIn coal mines, harsh environments and complex geological conditions underground lead to frequent failures of tunnel drilling rigs. However, conventional techniques for failure diagnosis and early warning suffer from limitations in diagnostic ...
Haitao SONG, Naiwen ZHANG, Jian HAN, Min WU   +3 more
doaj   +1 more source

Factors associated with early failure of the femoral neck system (FNS) in patients with femoral neck fractures. [PDF]

BMC Musculoskelet Disord, 2023
Chen L, Jiang JB, Ma H, Duan X, Chen JL.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Metallurgical investigation of early failure of heater pipes in a gas complex. [PDF]

Sci Rep, 2023
Khalifa W, El-Hadad S.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Catastrophic Early Failure and Fragmentation of a Modern Moderately Cross-linked Polyethylene Acetabular Liner. [PDF]

Arthroplast Today, 2023
Barakat N, Browne JA, Cui Q.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Set of heart failure early mortality prevention methods

Healthcare in Low-resource Settings
Heart failure is a common chronic disease with a poor prognosis that often ends in death. The research thus aims to thoroughly investigate ways in which the prognosis of heart failure could be improved.
Boguslawa Serzysko, Renata Mroczkowska, Beata Podsiadlo, Boguslawa Kupczak Wisniewska   +3 more
doaj   +1 more source