Results 81 to 90 of about 1,564,555 (265)

TREATMENT OF EARLY STAGES OF HEART FAILURE

Российский кардиологический журнал, 2001
We performed a complex study of central, cardiac and peripheral regional hemodynamics (PRH), neurohumoral activity, tolerance to dosed physical stress, as wells life quality evaluation and comparative efficacy of long-term (12 months) sole7 treatment ...
V. I. Vishnevsky
doaj  

Construction of management tools for early warning of prevacuum steam sterilization failure.

PLoS ONE
ObjectiveThe aim of this study is to develop a set of management tools for early warning of steam sterilization failure, including a failure risk checklist and a calculation model for assessing early sterilization failure risk, and to verify the early ...
Xin Zhao, Ting Liu, Ning Ma, Ran Wang, Ying Li, Tong Shen   +5 more
doaj   +1 more source

Acupuncture and Kinesitherapy Improve Physical Activity More than Kinesitherapy Alone in Patients with Acute Decompensated Chronic Heart Failure with Reduced Ejection Fraction Who Are Already on Optimal Drug Therapy: A Randomized, Sham-Controlled, Double-Blind Clinical Study

Biomedicines
Background/Objectives: It is unknown how early exercise therapy combined with acupuncture (AP) affects the speed of recovery in patients suffering from heart failure with reduced ejection fraction (HFrEF) who are hospitalized due to worsening HF. Methods:
Dejan Ilic, Zoran Jovic, Zorica Mladenovic, Vesna Pejovic, Branislava Lung, Aleksandra Kozic, Slobodan Obradovic   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Not all meniscal repair failures are equal: A comparison between early and late failure risk factors

Journal of Experimental Orthopaedics
Purpose Meniscal repair failure is a significant clinical concern, but existing literature treats it as a single outcome without differentiating timing.
Jacob W. McDevitt, Thomas J. Policicchio, Anoop Sunkara, Cade F. Bennett, Michael O. Sohn, Jake A. Morales, Vehniah K. Tjong   +6 more
doaj   +1 more source

Are the Post-transplant Outcomes of Kasai's Early Failure and Late Failure Comparable to the Primary Liver Transplantation? [PDF]

Cureus, 2023
Sanha V, Franzini TA, Junior WF, Kalil AN.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Validation of recipient-specific kinetic prediction scores for allograft failure after liver transplantation: a single centre retrospective analysis

BMC Gastroenterology
Liver transplantation remains the definitive therapy for end-stage liver disease, yet Early Allograft Dysfunction (EAD) continues to challenge post-transplant outcomes.
Alexandru Marinescu, Mihaela Oliță, Andrei Moroianu, Andrei Vasilescu, Iulia-Alexandra Tutoveanu, Alexandra Marinescu, Vladislav Brașoveanu, Emmanuel Weiss, Dana Tomescu   +8 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source