Results 201 to 210 of about 11,648,449 (278)

Early goal-directed therapy reduces mortality in adult patients with severe sepsis and septic shock: Systematic review and meta-analysis. [PDF]

Indian J Crit Care Med, 2015
Chelkeba L, Ahmadi A, Abdollahi M, Najafi A, Mojtahedzadeh M.   +4 more
europepmc   +1 more source

Impact of goal-directed fluid therapy on early cognitive function after one-lung ventilation in the elderly

Asian Journal of Surgery
Li Yuan, Xiangbo Li, Yanlin Chen, Jinliang Teng   +3 more
doaj   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Effect of early goal directed therapy on tissue perfusion in patients with septic shock. [PDF]

World J Emerg Med, 2013
Lu YH, Liu L, Qiu XH, Yu Q, Yang Y, Qiu HB.   +5 more
europepmc   +1 more source

Topology‐Driven X‐Shaped DNA as a cGAS Stimulator to Promote Dendritic Cell Activation and Antitumor Vaccine Efficacy

Advanced Science, EarlyView.
X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li, Xuan Wang, Dali Wei, Zhejie Chen, Ziyi Wang, Qing Yu, Yu Yang, Shengpeng Wang   +7 more
wiley   +1 more source

Rethinking Cochlear Implants: The Need for Precise Temporal Coding

Advanced Science, EarlyView.
Spatial hearing relies on sensitivity to interaural temporal cues, but this sensitivity is often poorly developed in patients with cochlear implants, particularly those with early‐onset hearing loss. Rats with cochlear implants, however, demonstrate excellent temporal sensitivity, suggesting that this limitation is not inevitable.
Nicole Rosskothen‐Kuhl, Jan W. H. Schnupp   +1 more
wiley   +1 more source

Roles of Interstitial Albumin in the Subcutaneous Delivery of Therapeutic Peptides

Advanced Science, EarlyView.
A biomimetic extracellular matrix hydrogel platform reveals how interstitial albumin regulates peptide pharmacokinetics after subcutaneous administration. Albumin not only binds peptides but also shows a unique affinity for glycosaminoglycans, thereby reshaping peptide distribution and diffusion.
David Juriga, Anton Norberg, Esther Olaniran Håkansson, Jeroen W. van den Heuvel, Johan Gråsjö, Luke R. Odell, Anna Orlova, Per Hansson   +7 more
wiley   +1 more source

Prognostic utility of plasma lactate measured between 24 and 48 h after initiation of early goal-directed therapy in the management of sepsis, severe sepsis, and septic shock. [PDF]

J Intensive Care, 2016
Chertoff J, Chisum M, Simmons L, King B, Walker M, Lascano J.   +5 more
europepmc   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

Advanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source