Results 201 to 210 of about 292,316 (287)

Correction for Forrest et al., Early evidence for a stable and flexible foraging niche in the evolution of <i>Homo</i>. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

The Natural History of Periodontitis in Man: The Past, the Present, the Future. [PDF]

J Periodontal Res
van der Velden U, Danser MM.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

No evidence that hominin dispersal across Eurasia was part of a wider turnover in mammal distributions. [PDF]

Nat Commun
Sun J, de la Torre I, Bibi F.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

What Is the Acheulean? [PDF]

Evol Anthropol
Moncel MH, Cucart-Mora C, Arzarello M, Ashton N, Baena J, Barsky D, de la Torre I, Galanidou N, García-Medrano P, Hertler C, Herzlinger G, Ingicco T, Li H, Ma D, Mosquera M, Ollé A, Pappu S, Pei S, Tian C, Wang W, Bae CJ.   +20 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Genome sequences of 15 <i>Escherichia coli</i> O77g strains related to an emerging STEC lineage. [PDF]

Microbiol Resour Announc
Tran M-L, Vorimore F, Fach P, Delannoy S.   +3 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

<i>NPHS2</i> Revisited Through 208 Cases and Podocin Complex Modeling. [PDF]

Kidney Int Rep
Mertens ND, Nicolas Frank C, Bolsius L, Shril S, Majmundar AJ, Huber TB, Hildebrandt F, Buerger F.   +7 more
europepmc   +1 more source