Results 101 to 110 of about 1,850,573 (315)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Talent identification and development: an academic review. [PDF]

, 2002
The Academic Review was commissioned to help evaluate Sportscotland's pilot Talent Identification and Development Programme which operated from early 2000 to the end of 2001.
Sowerby, Katie, Collins, Dave, Abbott, Angela, Martindale, Russell J J   +3 more
core  

An advanced Artificial Intelligence platform for a personalised treatment of Eating Disorders

Frontiers in Psychiatry
IntroductionEating Disorders (EDs) affect individuals globally and are associated with significant physical and mental health challenges. However, access to adequate treatment is often hindered by societal stigma, limited awareness, and resource ...
Francesco Monaco, Francesco Monaco, Annarita Vignapiano, Annarita Vignapiano, Martina Piacente, Claudio Pagano, Carlo Mancuso, Luca Steardo, Alessandra Marenna, Federica Farina, Gianvito Petrillo, Stefano Leo, Emanuela Ferrara, Stefania Palermo, Vassilis Martiadis, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Alessio Maria Monteleone, Alessio Fasano, Alessio Fasano, Alessio Fasano, Giulio Corrivetti, Giulio Corrivetti   +25 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Leveraging Convolutional Neural Networks for Disease Detection in Vegetables: A Comprehensive Review

Agronomy
Timely and accurate detection of diseases in vegetables is crucial for effective management and mitigation strategies before they take a harmful turn.
Muhammad Mahmood ur Rehman, Jizhan Liu, Aneela Nijabat, Muhammad Faheem, Wenyuan Wang, Shengyi Zhao   +5 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Development and Internal Validation of an Early Warning Predictive Model for Critically Ill Patients in the Emergency Department Utilizing Easily Obtainable Clinical Indicators

Risk Management and Healthcare Policy
Xurui Li,* Jian Lv,* Hui Guo, Hongling Li, Qian Zhao, Huijun Qi, Jianguo Li Department of Emergency, Hebei General Hospital, Shijiazhuang, People’s Republic of China*These authors contributed equally to this workCorrespondence ...
Li X, Lv J, Guo H, Li H, Zhao Q, Qi H, Li J   +6 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets

, 2018
Qian Chen,1 Xiaoyun Zeng,2 Dongping Huang,2 Xiaoqiang Qiu2 1Department of Research, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China; 2Department of Epidemiology, School of Public Health, Guangxi Medical University ...
Chen Q, Huang D, Qiu X, Zeng X
core  

Feasibility of a 2-minute eye-tracking protocol to support the early identification of autism

We tested the potential for Gazefinder eye-tracking to support early autism identification, including feasible use with infants, and preliminary concurrent validity of trial-level gaze data against clinical assessment scores.
Boutrus, M, Bent, CA, Whitehouse, AJO, Chetcuti, L, Hudry, K, Smith, J, Varcin, KJ   +6 more
core   +1 more source