Results 111 to 120 of about 19,801,094 (386)

Low-temperature thermochronology and its geological significance in the central-northern section of the western margin of the Ordos Basin [PDF]

open access: yesSolid Earth
The study of low-temperature thermochronology at plate edges provides favourable constraints for regional tectonic evolution and surface processes. Based on the existing thermochronological data of multiple cooling events since the Mesozoic era, we ...
G. Xing   +11 more
doaj   +1 more source

Paleolakes and life on early Mars [PDF]

open access: yes
Two distinct directions have begun to elucidate key parameters in the search for extinct life on Mars. Carbonate sediments, deposited about 10,000 years ago in association with biological activity, have been sampled from the paleolake beds of Lake Vanda ...
Mckay, C. P.   +2 more
core   +1 more source

The composition of the gut microbiota throughout life, with an emphasis on early life

open access: yesMicrobial Ecology in Health and Disease, 2015
The intestinal microbiota has become a relevant aspect of human health. Microbial colonization runs in parallel with immune system maturation and plays a role in intestinal physiology and regulation. Increasing evidence on early microbial contact suggest
J. M. Rodríguez   +11 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Earliest ontogeny of early Cambrian acrotretoid brachiopods — first evidence for metamorphosis and its implications

open access: yesBMC Evolutionary Biology, 2018
Background Our understanding of the ontogeny of Palaeozoic brachiopods has changed significantly during the last two decades. However, the micromorphic acrotretoids have received relatively little attention, resulting in a poor knowledge of their ...
Zhiliang Zhang   +3 more
doaj   +1 more source

Mild early‐life stress exaggerates the impact of acute stress on corticolimbic resting‐state functional connectivity [PDF]

open access: hybrid, 2021
Huan Wang   +6 more
openalex   +1 more source

Early Childhood Education: Frozen Funding Leads to Cracks in Foundation [PDF]

open access: yes, 2012
Early childhood education is the cornerstone of our educational system. With benefits that include higher academic achievement, higher earnings as adults, a more productive civic life, high quality early childhood education is a proven-to-work strategy ...
Marina Marcou-O'Malley
core  

Gender differences in the pathways from childhood disadvantage to metabolic syndrome in adulthood: An examination of health lifestyles. [PDF]

open access: yes, 2018
We investigate whether socioeconomic status (SES) in childhood shapes adult health lifestyles in domains of physical activity (leisure, work, chores) and diet (servings of healthy [i.e., nutrient-dense] vs. unhealthy [energy-dense] foods).
Boylan, Jennifer M   +3 more
core   +3 more sources

The Impact of IgG Transplacental Transfer on Early Life Immunity

open access: yesImmunoHorizons, 2018
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but as protective immunity often requires several infant vaccine doses, maternally acquired Abs are critical to protect infants during the first months of life ...
G. Fouda   +3 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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