Low-temperature thermochronology and its geological significance in the central-northern section of the western margin of the Ordos Basin [PDF]
The study of low-temperature thermochronology at plate edges provides favourable constraints for regional tectonic evolution and surface processes. Based on the existing thermochronological data of multiple cooling events since the Mesozoic era, we ...
G. Xing +11 more
doaj +1 more source
Paleolakes and life on early Mars [PDF]
Two distinct directions have begun to elucidate key parameters in the search for extinct life on Mars. Carbonate sediments, deposited about 10,000 years ago in association with biological activity, have been sampled from the paleolake beds of Lake Vanda ...
Mckay, C. P. +2 more
core +1 more source
The composition of the gut microbiota throughout life, with an emphasis on early life
The intestinal microbiota has become a relevant aspect of human health. Microbial colonization runs in parallel with immune system maturation and plays a role in intestinal physiology and regulation. Increasing evidence on early microbial contact suggest
J. M. Rodríguez +11 more
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Background Our understanding of the ontogeny of Palaeozoic brachiopods has changed significantly during the last two decades. However, the micromorphic acrotretoids have received relatively little attention, resulting in a poor knowledge of their ...
Zhiliang Zhang +3 more
doaj +1 more source
Mild early‐life stress exaggerates the impact of acute stress on corticolimbic resting‐state functional connectivity [PDF]
Huan Wang +6 more
openalex +1 more source
Early Childhood Education: Frozen Funding Leads to Cracks in Foundation [PDF]
Early childhood education is the cornerstone of our educational system. With benefits that include higher academic achievement, higher earnings as adults, a more productive civic life, high quality early childhood education is a proven-to-work strategy ...
Marina Marcou-O'Malley
core
Gender differences in the pathways from childhood disadvantage to metabolic syndrome in adulthood: An examination of health lifestyles. [PDF]
We investigate whether socioeconomic status (SES) in childhood shapes adult health lifestyles in domains of physical activity (leisure, work, chores) and diet (servings of healthy [i.e., nutrient-dense] vs. unhealthy [energy-dense] foods).
Boylan, Jennifer M +3 more
core +3 more sources
The Impact of IgG Transplacental Transfer on Early Life Immunity
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but as protective immunity often requires several infant vaccine doses, maternally acquired Abs are critical to protect infants during the first months of life ...
G. Fouda +3 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

