Results 91 to 100 of about 13,584,933 (301)

Delaware Early Childhood Council 2011 Annual Report

open access: yes, 2012
2011 Annual Report of the Delaware Early Childhood ...
Delaware Early Childhood Council
core   +2 more sources

Formation of a typical landslide-debris flow disaster chain induced by rainstorm

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Due to global warming, the Qinba Mountain Area in China has experienced frequent extreme heavy rainfall events, transforming isolated geological hazards into multi-hazard chains characterized by cascading and compound disasters.
An Zhao   +6 more
doaj   +1 more source

Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention [PDF]

open access: yes, 2015
Background: early life may be a “critical period” when appetite and regulation of energy balance are programmed, with lifelong consequences for obesity risk.
Crozier, Sarah   +15 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

New reconstruction of the Wiwaxia scleritome, with data from Chengjiang juveniles

open access: yesScientific Reports, 2015
Wiwaxiids are a problematic group of scale-covered lophotrochozoans known from Cambrian Stages 3–5. Their imbricating dorsal scleritome of leaf-like scales has prompted comparison with various annelids and molluscs and has been used as a template to ...
Zhifei Zhang, Martin R. Smith, Degan Shu
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Sustaining Early Success: Delaware’s Strategic Plan for a Comprehensive Early Childhood System

open access: yes, 2013
2013 Annual Report and Strategic Plan of the Delaware Early Childhood ...
Delaware Early Childhood Council
core   +1 more source

Characteristics and modeling of natural fractures under compressive stress field: a case study of the eighth member of the upper paleozoic shihezi formation in southern Sulige

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
This study focuses on the natural fracture system in the tight, low-porosity, and low-permeability He 8 Member of the Shihezi Formation in the southern Sulige Gas Field, exploring fracture development characteristics, spatial distribution, and gas–water ...
Zhiqiang Chen   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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