Results 211 to 220 of about 8,229,253 (288)

Early Life Adversity and Disordered Eating: Cognitive and Neural Mechanisms. [PDF]

Behav Sci (Basel)
Luo Y, Zhang J, Chen H.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Early-life microbiota disruption-induced deficits in the social brain are sensitive to diet. [PDF]

iScience
Ratsika A, Bergmann CA, Valderrama B, Bastiaanssen TFS, Sharvin BL, Renes IB, Knol J, Gunnigle E, Clarke G, Cryan JF.   +9 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Persistent effects of early-life arsenic exposure in <i>Caenorhabditis elegans</i>.

Environ Sci Process Impacts
Hershberger KA, Gaballah S, He BJ, Zhang L, Barefoot-Gautier E, Reed CB, Rivera NA, Hsu-Kim H, Meyer JN.   +8 more
europepmc   +1 more source

Effects of specialized proresolving mediators on gut epithelial barrier in early life. [PDF]

J Pharmacol Exp Ther
Chen J, Ouahoud S, Schreurs RRCE, Meisner S, Vermeulen JLM, Wildenberg ME, de Jonge WJ, van Goudoever JB, de Meij TGJ, Muncan V, van den Akker CHP.   +10 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Early life group 2 innate lymphoid cells in health and disease. [PDF]

Mol Cell Pediatr
Duerr CU, Mall MA.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source