Results 91 to 100 of about 4,035,262 (238)

Early-life stress and neurometabolites of the hippocampus [PDF]

Brain Research, 2010
We tested the hypothesis that early life stress would persistently compromise neuronal viability of the hippocampus of the grown nonhuman primate. Neuronal viability was assessed through ascertainment of N-acetyl aspartate (NAA)-an amino acid considered reflective of neuronal density/functional integrity-using in vivo proton magnetic resonance ...
Jeremy D, Coplan, Sanjay J, Mathew, Chadi G, Abdallah, Xiangling, Mao, John G, Kral, Eric L P, Smith, Leonard A, Rosenblum, Tarique D, Perera, Andrew J, Dwork, Patrick R, Hof, Jack M, Gorman, Dikoma C, Shungu   +11 more
openaire   +2 more sources

Differential impact of Met receptor gene interaction with early-life stress on neuronal morphology and behavior in mice

Neurobiology of Stress, 2018
Early adversity in childhood increases the risk of anxiety, mood, and post-traumatic stress disorders in adulthood, and specific gene-by-environment interactions may increase risk further.
Hanke Heun-Johnson, Pat Levitt
doaj   +1 more source

Perturbations in growth trajectory due to early diet affect age-related deterioration in performance [PDF]

, 2015
Fluctuations in early developmental conditions can cause changes in growth trajectories that subsequently affect the adult phenotype. Here, we investigated whether compensatory growth has long-term consequences for patterns of senescence.
Galloway T.F., Metcalfe N.B., Partridge L., Roff D.A., Rose M.R., Samuels S.E., Sogard S.M., Stearns S.C., Team, R.D.C.   +8 more
core   +2 more sources

Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms

Molecular Psychiatry, 2019
Exposure to stress during early life (infancy/childhood) has long-term effects on the structure and function of the prefrontal cortex (PFC), and increases the risk for adult depression and anxiety disorders.
A. Teissier, C. Le Magueresse, J. Olusakin, Belmira L. S. Andrade da Costa, A. M. De Stasi, A. Bacci, Y. Imamura Kawasawa, V. Vaidya, P. Gaspar   +8 more
semanticscholar   +1 more source

Early life stress and altered social behaviors: A perspective across species

Neuroscience Research
Childhood and adolescent affiliations guide how individuals engage in social relationships throughout their lifetime and adverse experiences can promote biological alterations that facilitate behavioral maladaptation.
Lyonna F. Parise, C. Joseph Burnett, Scott J. Russo   +2 more
doaj   +1 more source

Qué sabemos sobre las consecuencias a largo plazo de la separación materna temprana y la respuesta neuroendocrina al estrés [PDF]

, 2014
Adverse conditions during early life are a risk factor for stress-related diseases. How this early adversity induce long-term effects is not well understood, however there are several evidence that the stress hormones play a determining role.
Renard, Georgina Maria, Rivarola, María Angélica   +1 more
core  

How is mortality affected by money, marriage, and stress? [PDF]

, 2004
It is believed that the length of a person’s life depends on a mixture of economic and social factors. Yet the relative importance of these is still debated.
Gardner, Jonathan, Oswald, Andrew J.
core   +1 more source

Emerging roles of epigenetic mechanisms in the enduring effects of early-life stress and experience on learning and memory. [PDF]

, 2011
Epigenetic mechanisms are involved in programming gene expression throughout development. In addition, they are key contributors to the processes by which early-life experience fine-tunes the expression levels of key neuronal genes, governing learning ...
Baram, Tallie Z, Cope, Jessica, Ivy, Autumn, Korosi, Aniko, McClelland, Shawn   +4 more
core   +1 more source

The effects of early life stress on reward processing.

Journal of Psychiatric Research, 2018
Early life stress (ELS), in the form of childhood maltreatment, abuse, or neglect, increases the risk for psychiatric sequelae later in life. The neurobiology of response to early stress and of reward processing overlap substantially, leading to the ...
A. Novick, M. L. Levandowski, Laura E Laumann, N. Philip, L. Price, A. Tyrka   +5 more
semanticscholar   +1 more source

Childhood adversity and psychopathology: the dimensions of timing, type and chronicity in a population-based sample of high-risk adolescents

Child and Adolescent Psychiatry and Mental Health
Background Research on childhood adversity and psychopathology has begun investigating the dimension of timing, however the results have been contradictory depending on the study population, outcome and how adverse life events (ALEs) were operationalized.
Milan Zarchev, Nina H. Grootendorst-van Mil, Diandra C. Bouter, Witte J. G. Hoogendijk, Cornelis L. Mulder, Astrid M. Kamperman   +5 more
doaj   +1 more source