Results 191 to 200 of about 16,479 (293)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Internal shifting impairments in response to emotional information in dysphoric adolescents [PDF]

open access: yes, 2017
Braet, Caroline   +4 more
core   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

Social Isolation Trajectories Spanning Childhood to Adulthood and Mortality Risk in CKM Syndrome: Evidence From CHARLS

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
ABSTRACT Background Social isolation is increasingly recognized as a critical determinant of health. This study aimed to systematically evaluate the association between social isolation trajectories spanning childhood to adulthood and all‐cause mortality in patients with cardiovascular‐kidney‐metabolic (CKM) syndrome stages 1–4 and to investigate the ...
Luyue Liang   +3 more
wiley   +1 more source

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