Stable neuronal representations underlie cognitive resilience to Alzheimer's disease pathology
Abstract INTRODUCTION While Alzheimer's disease (AD) typically elicits progressive cognitive decline, some individuals with significant AD pathology maintain cognition. Understanding the neuronal underpinnings of such cognitive resilience would propel the development of interventions for delaying dementia.
Keying Chen +9 more
wiley +1 more source
The association between early maladaptive schemas and romantic relationship satisfaction. [PDF]
Kover L +5 more
europepmc +1 more source
Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
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Childhood abuse and maladaptive coping in care leavers: An exploratory study on attachment and Early Maladaptive Schemas. [PDF]
Jarvis M +3 more
europepmc +1 more source
ABSTRACT Objective With increasing long‐term survival among brain tumor patients, greater attention has shifted to disease‐related physiological and psychological challenges. This study aimed to describe illness perceptions and psychosocial adjustment in brain tumor patients and their primary caregivers; analyze dyadic actor‐partner interdependence ...
Ting Huang +5 more
wiley +1 more source
The Mediating Role of Early Maladaptive Schemas in the Relationship Between Attachment Styles and Adjustment to Early-Stage Breast Cancer. [PDF]
Karveli S +5 more
europepmc +1 more source
ABSTRACT Purpose The therapeutic alliance (TA) can be conceptualised in terms of three interrelated elements: (a) agreement between therapist and client about the goals of the treatment, (b) agreement between therapist and client about the necessary tasks to achieve the goals, and (c) a bond between therapist and client.
Helen J. Wall, Sarah Mather
wiley +1 more source
Time Perspective Prediction Based on Early Maladaptive Schemas Mediated by Life Expectancy Among University Students: A Cross-Sectional Study. [PDF]
Abedi Yarandi MS, Madahi ME.
europepmc +1 more source
This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou +7 more
wiley +1 more source
Early maladaptive schemas from child maltreatment in depression and psychotherapeutic remediation: a predictive coding framework. [PDF]
Ramamurthy G, Chen A.
europepmc +1 more source

