Results 221 to 230 of about 5,057,518 (281)

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Beliefs about emotions, distress tolerance and paranoia across the menstrual cycle in individuals with premenstrual difficulties and controls

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Premenstrual Disorders are characterized by recurrent symptoms associated with clinically significant distress or impairment. There is limited understanding of psychological processes associated with premenstrual difficulties.
Ellen Lambert, Myra Hunter, Trudie Chalder   +2 more
wiley   +1 more source

The Down's Syndrome Neurocognitive Change Monitoring Framework (DS‐NCMF): A Clinical Reasoning Framework for Emerging Neurocognitive Change

British Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Adults with Down's syndrome face a high lifetime risk of Alzheimer's disease, yet existing assessment instruments and clinical guidance do not structure how longitudinal caregiver observations are interpreted and acted upon before formal specialist assessment.
Daniel Acton, Mrityunjai Kumar, Sujeet Jaydeokar   +2 more
wiley   +1 more source

Association of Life's Essential 8 Score With Incident Pancreatic Cancer: A Prospective Cohort Study in Shanghai, China

Cancer Science, EarlyView.
In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi, Xing Liu, Maryam Zaid, Kexin Zhang, Biying Wang, Yingqi Deng, Minhua Tang, Yonggen Jiang, Genming Zhao   +8 more
wiley   +1 more source

Understanding Rheumatoid Arthritis‐Oral Health Perceptions Around Diagnosis and the Early Disease Course: A Phenomenological Approach

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To explore how Dutch adults with rheumatoid arthritis (RA) perceive their oral health around the diagnostic process and the early disease course. The primary objective was to describe these perceptions in depth, and a secondary objective was to identify areas for future patient‐centred research.
Nadine Isabel Bhagwandas, Lotte Arwen van de Stadt, Johanna Margaretha Kroese   +2 more
wiley   +1 more source