Results 231 to 240 of about 145,683 (294)
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong +5 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To evaluate whether the IOTA ADNEX model and the Two‐Step Strategy improve triage and referral of adnexal masses in routine gynaecologic care compared with the RMI and to identify an appropriate malignancy‐risk threshold. Design Prospective multicenter cohort study. Setting Thirteen non‐tertiary hospitals and clinics and one tertiary
Nikoline Schou Karlsen +9 more
wiley +1 more source
Asia-Pacific Journal of Clinical Oncology, EarlyView.This retrospective study of patients with small, node‐negative HER2+ breast cancer found favorable 5‐year invasive disease‐free survival rates—93% for pT1mic/a disease and 100% for pT1b disease. Trastuzumab was administered to 66% of patients and was associated with larger tumor size and higher histologic grade.
Yuanyuan Xue +5 more
wiley +1 more source
Australasian Journal of Dermatology, EarlyView.ABSTRACT There have only been a limited number of case reports that have described vulval lichen sclerosus in patients receiving immune checkpoint inhibitor (ICI) therapy. We describe 11 cases of vulval lichen sclerosus in patients with melanoma treated with ICIs, and in nine of these cases, the lichen sclerosus symptoms began after ICI commencement ...
Sophie Walter +9 more
wiley +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, EarlyView.ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population
Allergy, EarlyView.The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard +10 more
wiley +1 more source
ANZ Journal of Surgery, EarlyView.ABSTRACT Background Undertriage of women with trauma is associated with preventable deaths. This project was developed to determine whether older women with trauma were less likely to be admitted to a specialist trauma unit. Methods The study was undertaken at a specialist, level one trauma service and included all people aged 65 and older admitted ...
Katherine Gregorevic +4 more
wiley +1 more source
ANZ Journal of Surgery, EarlyView.Anti‐reflux and paraoesophageal hernia surgery rates in Australia rose markedly from 2000 to 2024, especially among females and older adults. Hiatal closure procedures increased while isolated fundoplasty declined, highlighting shifting surgical practice and notable sex‐ and age‐related differences in treatment patterns.
Christopher Goubar +3 more
wiley +1 more source