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Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard +10 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Nalini Kaushik +2 more
wiley +1 more source
Summary Introduction Prehabilitation has become increasingly prominent in the context of cancer surgery. While prehabilitation offers significant benefits, it can also inadvertently broaden inequalities because it is often more accessible to some than others.
Charlotte Hadley +11 more
wiley +1 more source
Sugammadex interference with serum progesterone measurement: an in‐vitro study
Summary Introduction Sugammadex may interfere with serum progesterone immunoassays, potentially rendering measured concentrations and resulting recommendations unreliable. Methods We investigated the effect of a range of sugammadex concentrations on serum progesterone concentrations in samples from pre‐menopausal female volunteers.
Tamblyn Devoy +5 more
wiley +1 more source
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon +3 more
wiley +1 more source
Optimising health after early menopause
The typical age at menopause is 50-51 years in high-income countries. However, early menopause is common, with around 8% of women in high-income countries and 12% of women globally experiencing menopause between the ages of 40 years and 44 years. Menopause before age 40 years (premature ovarian insufficiency) affects an additional 2-4% of women.
Martha Hickey +2 more
exaly +6 more sources
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Premature ovarian insufficiency, early menopause, and induced menopause
Best Practice and Research in Clinical Endocrinology and MetabolismPremature ovarian insufficiency (POI) is a condition in which there is a decline in ovarian function in women who are younger than 40 years resulting in a hypo-oestrogenic state with elevated gonadotrophins and oligomenorrhoea/amenorrhoea. This leads to short term complications of menopausal symptoms and long-term effects on bone and cardiovascular ...
Haitham Hamoda
exaly +3 more sources
Family history as a predictor of early menopause
Fertility and Sterility, 1995To determine the relative importance of family history as a predictor of early menopause.Case-control study. From a population-based survey of 10,606 women between 45 and 54 years of age, we selected 344 cases with early menopause (average age 42.2 years) and 344 age-matched controls who were still menstruating or who had a menopause after age 46 years.
Bernard Harlow, Daniel Cramer
exaly +3 more sources

