Results 31 to 40 of about 2,848,670 (398)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
“A Mirror for Men” – Reconstructing a Medieval Polishing Bench and Putting it to the Test
EXARC Journal, 2020 In the late 5th century AD, the famous Ostrogoth Theoderic the Great received a truly regal gift from the king of the Warini: he was given highly elaborated swords, richly decorated and able to cut through armour.
Florian Messner
doaj
Stage Based Interventions for Low Fat Diet with Middle School Students [PDF]
, 2003 Preventing obesity and cardiovascular disease at early ages is important; however, few effective interventions for early adolescents have been reported. In this study, low-income, culturally diverse students from an urban middle school (n = 60) received ...
Bansal, Naveen K. +2 more
core +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Київські історичні студіїThe article examines the feasibility of applying the concepts of “centralization” of Muscovy and “new period of Russian history” in the 16th and 17th centuries, respectively.
Oleksandr Hurzhii, Vitalii Shcherbak
doaj +1 more source
Grooming the Face in the Early Middle Ages
Internet Archaeology, 2016 A study of beards and hair focusing on the medieval period in Europe. There is a brief introduction looking at the modern period and how it contrasts with beards in the past.
Steven P. Ashby
doaj +1 more source
TETIUSHI-II HILLFORT — AN URBAN-TYPE SETTLEMENTOF THE EARLY MIDDLE AGES
Теория и практика археологических исследований, 2023 The article deals with the issues related to the problem of the existence of urban-type settlements in the Early Middle Ages in the Volga-Kama. On the example of the materials of TetiushiII hillfort located on the right bank of the Volga, the author ...
К.А. Руденко
doaj +1 more source
Thinking in Islands; the Portuguese Perception of the Indonesian Archipelago and Particularly of Sunda in Early Texts and Charts [PDF]
, 2012 This article discusses various early sources on the Indonesian archipelago. It starts with the status of knowledge before the first voyage of the Portuguese to the Moluccas from accounts of travellers to insular Southeast Asia in the Middle Ages and the ...
Langguth, S. (Svann)
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source