Results 141 to 150 of about 5,350,794 (320)

Early childhood flexibility practices and patterns: report 2014 [PDF]

, 2014
The Early childhood flexibility practices and patterns report highlights recommendations and future directions for early childhood education and care (ECEC) services in providing flexible arrangements for families and local communities.
Early Childhood Australia
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Standards of care for people with non-physically disabling neurological (and associated psychiatric) conditions.

, 2001
The standards of care recommended within this document are based on the collective experiences and recommendations of the Neurological Alliance of Ireland, in conjunction with members of the Elan Neurology Advisory Board (see Appendix B).
Neurological Alliance of Ireland
core  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

An online collection of information issued by the Kansas Neurological Institute (KNI), 1997-2008

, 1997
The information in this collection was collected primarily from the Kansas Neurological Institute's 2002-2008 websites, harvested from the WayBack Machine.
Kansas Neurological Institute.
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Temporary Neurological Deterioration after Extracranial-Intracranial Bypass

, 1984
Five patients who experienced temporary neurological deterioration after extracranial to intracranial bypass procedures are reported in detail. These patients suffered transient ischemic attacks or more prolonged deficits usually of a different nature ...
Heros, Roberto C, Conner, Scott E, Scott, Michael R, Ackerman, Robert H, Kistler, Philip J   +4 more
core   +1 more source

Neutrophil Lymphocyte Ratio Predicts Early Neurological Deterioration in Patients with Anterior Circulation Stroke

International Journal of General Medicine
Lingling Zhao,1,* Shuyu Zhou,1,* Qiliang Dai,2 Junrong Li1 1Department of Neurology, The Affiliated Jiangning Hospital of Nanjing Medical University, Jiangning Clinical Medical School, Kangda College of Nanjing Medical University, Nanjing, People’
Zhao L, Zhou S, Dai Q, Li J
doaj  

Prognostic Significance of Preoperative Neurological Versus Radiological Deterioration in Older Patients with Moderate-to-Mild Traumatic Brain Injury

Life
Background: The prognostic value of preoperative deterioration in older patients with moderate-to-mild traumatic brain injury (TBI) remains unclear.
Shin Heon Lee, Jong Tae Lee, Yong-sook Park   +2 more
doaj   +1 more source