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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Background Intracranial hemorrhage (ICH) is one of the main causes for lack of surgery in patients with infective endocarditis (IE), despite the presence of surgical indications.
Rita Musleh +7 more
doaj +1 more source
Early neurological deterioration after acute stroke.
The figure shows meta-analysis of early BP lowering on early neurological deterioration within 72 hours (A.) or within 14 days (B.) after acute stroke.
Hongxuan Wang (567669) +6 more
core +1 more source
Categorizing stroke prognosis using different stroke scales [PDF]
<p><b>Background and Purpose</b>: Stroke severity and dependency are often categorized to allow stratification for randomization or analysis. However, there is uncertainty whether the categorizations used for different stroke scales are
Langhorne, P., Govan, L., Weir, C.J.
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Diagnosis and treatment of paraneoplastic neurological disorders [PDF]
In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Voltz, R., Graus, F.
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Biochemical Indicators of Early Neurological Deterioration in Ischemic Stroke: A Hospital-Based Study. [PDF]
Title: Biochemical Indicators of Early Neurological Deterioration in Ischemic Stroke: A Hospital-Based Study.AbstractBackground: Understanding the cause of early neurological decline (END) subsequent to a cerebrovascular stroke can help direct the early ...
Mohammed Aly Ghonemy +1 more
doaj +1 more source
ObjectivesPatients with minor ischemic stroke (MIS) frequently suffer from early neurological deterioration (END) and become disabled. Our study aimed to explore the association between serum neurofilament light chain (sNfL) levels and END in patients ...
Xingyang Yi (4243381) +8 more
core +1 more source
Background and PurposeEarly neurological deterioration (END) occurs in 10% among patients with acute ischemic stroke (AIS) who are receiving intravenous thrombolysis (IVT).
Danfeng Zhang +8 more
doaj +1 more source

