Results 151 to 160 of about 1,485,041 (265)

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Early-onset Presbyopes: Functional Impact and the Need for Clinical Recognition. [PDF]

Ophthalmic Physiol Opt
Prenat O, Puar M, Rosenfield M.
europepmc   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Monoallelic POLR3A Variants Cause Early-Onset Peripheral Neuropathy. [PDF]

Ann Neurol
Ramos LLP, Parmar JM, Wijngaard R, Grosz BR, Lazar T, Mateiu L, Vucic S, Kumar KR, Yeow D, Rudaks LI, de Boer L, de Vreugd A, Koolen DA, Gardeitchik T, Cairns A, Iyengar K, Kok F, Figueiredo FB, de Siqueira Carvalho AA, Mageste Barbosa LS, Arantes RR, Rehbein T, Bontrager JE, Wood EP, Sowden JE, Monahan G, Kumaheri M, Cuijt I, Ellis M, Perez-Siles G, McNamara E, van Beek R, Meijers CB, Tournev I, Zuchner S, Wodak SJ, van Karnebeek CDM, Laing N, Semcesen LN, Stroud DA, Herrmann DN, Guergueltcheva V, Kennerson ML, Oud MM, Ravenscroft G, Candayan A, Jordanova A.   +46 more
europepmc   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Digital profiling of dysarthria in late- and early-onset Parkinson's disease. [PDF]

J Parkinsons Dis
Escobar-Grisales D, Rozenfeld Olchik M, Arias-Vergara T, Brzoskowski Dos Santos V, Lara Bressanelli A, Mata I, Orozco-Arroyave JR, García AM.   +7 more
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Dietary Fructose and Early-Onset Colorectal Cancer: Metabolic, Microbial, and Translational Perspectives. [PDF]

Microorganisms
Tangyingyong S, Abu-Fares H, Susiriwatananont T.   +2 more
europepmc   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Association of high birth weight with risk of early-onset colorectal cancer. [PDF]

Cancer Epidemiol Biomarkers Prev
Mukherjee A, Xu L, Getahun D, Chubak J, Figueiredo JC, Cannavale KL, Gilfillan AD, Wu BU, Chao CR.   +8 more
europepmc   +1 more source