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Regenerative medicine for early osteoarthritis [PDF]

open access: yesTherapeutic Advances in Musculoskeletal Disease, 2023
The concept of early osteoarthritis (OA) is based on the expectation that if found and treated in the early stage, the progression of the disease might be arrested before affected joints are irreversibly destroyed.
Gun-Il Im, Yves Henrotin
doaj   +4 more sources

Physical Agent Modalities in Early Osteoarthritis: A Scoping Review [PDF]

open access: yesMedicina, 2021
Early osteoarthritis (EOA) still represents a challenge for clinicians. Although there is no consensus on its definition and diagnosis, a prompt therapeutic intervention in the early stages can have a significant impact on function and quality of life ...
Giulia Letizia Mauro   +7 more
doaj   +3 more sources

Patellofemoral joint loading and early osteoarthritis after ACL reconstruction. [PDF]

open access: yesJ Orthop Res, 2023
Patellofemoral joint (PFJ) osteoarthritis is common following anterior cruciate ligament reconstruction (ACLR) and may be linked with altered joint loading.
Schache AG   +9 more
europepmc   +2 more sources

Infographic: Total hip arthroplasty in early osteoarthritis: picking your winners [PDF]

open access: yesBone & Joint Research, 2023
Cite this article: Bone Joint Res 2023;12(5):309–310.
Martin Sharrock, Tim Board
doaj   +2 more sources

The complexity of decision-making for total hip arthroplasty in early osteoarthritis [PDF]

open access: yesBone & Joint Research, 2023
Cite this article: Bone Joint Res 2023;12(5):306–308.
Martin Sharrock, Tim Board
doaj   +2 more sources

Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis [PDF]

open access: yesBone & Joint Research
Aims: Meniscal degeneration may precede or indicate early-stage osteoarthritis (OA); however, the pathogenetic involvement of the NF-κB pathway and its upstream IκB kinase (IKK) is unclear.
Ryota Hirose   +9 more
doaj   +2 more sources

Equine synovial fluid small non-coding RNA signatures in early osteoarthritis

open access: yesBMC Veterinary Research, 2021
Background Osteoarthritis remains one of the greatest causes of morbidity and mortality in the equine population. The inability to detect pre-clinical changes in osteoarthritis has been a significant impediment to the development of effective therapies ...
Catarina Castanheira   +9 more
doaj   +2 more sources

Inflammatory cytokines via up-regulation of aquaporins deteriorated the pathogenesis of early osteoarthritis.

open access: yesPLoS ONE, 2019
BackgroundInflammatory cytokines enhanced the progress of the pathogenesis of osteoarthritis, however the mechanisms remain unclear. The objective is to determine aquaporins (AQPs) in the pathogenesis of osteoarthritis.Methods and findingsPrimary rat ...
Chunjiang Tan   +11 more
doaj   +2 more sources

Knee Pain Expansion in Early Osteoarthritis: Findings from Iwaki Cohort Study [PDF]

open access: yesJournal of Pain Research
Ryo Tomita,1 Eiji Sasaki,1 Eitaro Sato,1 Yukiko Sakamoto,1 Yuka Kimura,1 Takahiro Tsushima,1 Eiichi Tsuda,2 Mizuri Ishida,3 Yasuyuki Ishibashi1 1Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan ...
Tomita R   +8 more
doaj   +2 more sources

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