Results 61 to 70 of about 7,641,894 (297)

Radiomics in FAI: current status and perspectives

Bone & Joint Research
Femoroacetabular impingement (FAI) is caused by abnormal contact between the femur and acetabulum, resulting in pain, limited motion, and early osteoarthritis. Existing imaging techniques for diagnosing FAI face considerable challenges.
Hariharan Subbiah Ponniah, Eros Montin, Srikar Namireddy, Riccardo Lattanzi, Kartik Logishetty   +4 more
doaj   +1 more source

Autologous mesenchymal stem cells or meniscal cells: what is the best cell source for regenerative meniscus treatment in an early osteoarthritis situation?

Stem cell research & therapeutics, 2017
Treatment of meniscus tears within the avascular region represents a significant challenge, particularly in a situation of early osteoarthritis. Cell-based tissue engineering approaches have shown promising results.
J. Zellner, G. Pattappa, M. Koch, S. Lang, J. Weber, C. Pfeifer, Michael B. Mueller, R. Kujat, M. Nerlich, P. Angele   +9 more
semanticscholar   +1 more source

Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis

Arthritis Research & Therapy, 2021
Background Investigating the pathophysiological mechanisms of early osteoarthritis (OA) is of utmost interest since this stage holds the strongest promise for therapeutic interventions.
N. Rosshirt, R. Trauth, H. Platzer, E. Tripel, T. Nees, H. Lorenz, T. Tretter, B. Moradi   +7 more
semanticscholar   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals with Type 2 Diabetes

Arthritis Care &Research, Accepted Article.
Objective Knee osteoarthritis (OA) commonly affects individuals with Type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Avoidance of Total Knee Arthroplasty in Early Osteoarthritis of the Knee with Intra-Articular Implantation of Autologous Activated Peripheral Blood Stem Cells versus Hyaluronic Acid: A Randomized Controlled Trial with Differential Effects of Growth Factor Addition

Stem Cells International, 2017
In this randomized controlled trial, in early osteoarthritis (OA) that failed conservative intervention, the need for total knee arthroplasty (TKA) and WOMAC scores were evaluated, following a combination of arthroscopic microdrilling mesenchymal cell ...
T. Turajane, U. Chaveewanakorn, W. Fongsarun, J. Aojanepong, K. Papadopoulos   +4 more
semanticscholar   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

T2 mapping of the meniscus is a biomarker for early osteoarthritis

European Radiology, 2019
PurposeTo evaluate in vivo T2 mapping as quantitative, imaging-based biomarker for meniscal degeneration in humans, by studying the correlation between T2 relaxation time and degree of histological degeneration as reference standard.MethodsIn this ...
S. Eijgenraam, Frans A. T. Bovendeert, J. Verschueren, J. van Tiel, Y. Bastiaansen‐Jenniskens, M. A. Wesdorp, K. Nasserinejad, D. Meuffels, Jamal Guenoun, S. Klein, M. Reijman, E. Oei   +11 more
semanticscholar   +1 more source

Establishing outcome measures in early knee osteoarthritis [PDF]

Nature Reviews Rheumatology, 2019
The classification and monitoring of individuals with early knee osteoarthritis (OA) are important considerations for the design and evaluation of therapeutic interventions and require the identification of appropriate outcome measures. Potential outcome domains to assess for early OA include patient-reported outcomes (such as pain, function and ...
Carolyn A. Emery, Jackie L. Whittaker, Armaghan Mahmoudian, L. Stefan Lohmander, Ewa M. Roos, Kim L. Bennell, Clodagh M. Toomey, Raylene A. Reimer, Dylan Thompson, Janet L. Ronsky, Gregor Kuntze, David G. Lloyd, Thomas Andriacchi, Martin Englund, Virginia B. Kraus, Elena Losina, Sita Bierma-Zeinstra, Jos Runhaar, George Peat, Frank P. Luyten, Lynn Snyder-Mackler, May Arna Risberg, Ali Mobasheri, Ali Guermazi, David J. Hunter, Nigel K. Arden   +25 more
openaire   +7 more sources

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

Arthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro, Karen Durrant, William G Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H Humphreys   +6 more
wiley   +1 more source