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Best Practice and Research in Clinical Endocrinology and Metabolism, 2002
Early puberty is not well defined in paediatric endocrinology. This chapter reviews the current insights on definitions, patient groups and treatment modalities in girls with early puberty. It is concluded that there is no clear evidence for a beneficial effect of gonadotrophin releasing hormone agonist (GnRHa) treatment in auxological terms.
D Mul, S L S Drop, W Oostdijk
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Early puberty is not well defined in paediatric endocrinology. This chapter reviews the current insights on definitions, patient groups and treatment modalities in girls with early puberty. It is concluded that there is no clear evidence for a beneficial effect of gonadotrophin releasing hormone agonist (GnRHa) treatment in auxological terms.
D Mul, S L S Drop, W Oostdijk
exaly +3 more sources
Early Puberty in Adopted Children
Hormone Research in Paediatrics, 2002Early puberty is frequently observed in adopted children. In various studies, early puberty has been associated with decreased final height. In Europe, studies were undertaken to treat early puberty in adopted children with GnRH agonist. This article reviews the current understanding of early puberty in adopted children, including prevalence ...
Mul, D (Dick) +2 more
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Early Influences on the Tempo of Puberty
Hormone Research in Paediatrics, 2006Fetal growth retardation appears to be associated with an increased risk of premature adrenarche, early puberty, polycystic ovary syndrome and associated fertility problems. In a rat model of intrauterine growth retardation, based on ligation of the uterine arteries, the onset of puberty was delayed in female pups, with anovulation during the first ...
M M, van Weissenbruch +1 more
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Early puberty in Williams syndrome
Clinical Dysmorphology, 1999Pubertal development was evaluated in nine males and 16 females with Williams syndrome (WS). Our results indicate that puberty in WS occurred earlier than in published population controls; specifically, 90% of menstruating females reached menarche and 83% of pubertal males showed Tanner III pubic hair development prior to the age of 12 years.
E M, Cherniske +4 more
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Early puberty, ‘sexualization’ and feminism
European Journal of Women's Studies, 2013Early onset puberty is increasingly prevalent among girls globally according to many scientists and clinicians. In the medical and scientific literature early sexual development is described as a problem for girls and as a frightening prospect for parents.
Celia Roberts
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Early Puberty and Childhood Social and Behavioral Adjustment
Journal of Adolescent Health, 2013Early puberty has been linked to higher rates of mental health problems in adolescence. However, previous studies commencing after the initiation of puberty have been unable to explore whether early puberty is preceded by higher rates of these problems.
Fiona Mensah +2 more
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Transient virilization in early puberty
Adolescent and Pediatric Gynecology, 1995Abstract A case report of a patient in whom transient elevation of androgens during early puberty, presumably physiologic, resulted in significant clitoral enlargement is presented. ACTH stimulation showed elevated A5 pathway steroids. The findings are consistent with partial 3-β-ol hydroxysteroid dehydrogenase deficiency.
J.E. Hersh +3 more
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Simplifying and refining the assessment of early puberty
Archives of Disease in Childhood, 2013Endogenous sex steroids can be produced in two places—the gonad or adrenal gland. The gonad in females primarily makes oestrogen and in males testosterone. A key physiological hallmark of puberty is the development of progressively rising pulsatile gonadotropin production by the pituitary gland.
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