Results 61 to 70 of about 887,011 (265)

To Identify High-Risk Adolescent and Adult Spinal Muscular Atrophy Populations: Exploration of Methods and Perspectives

罕见病研究
Spinal muscular atrophy(SMA)is a rare genetic neuromuscular disease characterized by significant clinical heterogeneity among patients. According to the severity and progression rate of the condition, the disease is classified into five types.
ZHAO Yuying, ZHU Wenhua, DAI Yi
doaj   +1 more source

Nucleotide-based green synthesis of lanthanide coordination polymers for tunable white-light emission

Green Processing and Synthesis, 2020
White-light emitting lanthanide(iii) metal-organic coordination polymers (LMOCPs) were prepared via a green synthesis method performed in pure aqueous solution at room temperature without using toxic solvent and reagents.
Zhang Yaoyao, Liu Baoxia, Shen Qi, Wei Xiuhua, Zhou Yanli, Zhang Yintang, Qu Peng, Xu Maotian   +7 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Comparison of 2005 and 2024 diagnostic criteria for early identification of pediatric sepsis and septic shock in PICU patients: a prospective cohort study

Frontiers in Pediatrics
BackgroundIn 2024, new international consensus criteria for pediatric sepsis and septic shock (2024 criteria) were introduced, replacing the 2005 criteria. The 2024 criteria use the Phoenix Sepsis Score (PSS) to define sepsis (score ≥2) and septic shock (
Wei Li, Wei Li, Haiyan Ge, Jin Zhang, Ning Li, Xiuxiu Lu, Jing Chen, Dong Qu, Shuang Liu, Chuanhe Liu, Chuanhe Liu   +10 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Intraoperative Cardiac Complications in Liver Transplantation: Preoperative Evaluation – A Narrative Review

Indian Journal of Transplantation
The decisive treatment for end-stage liver disease (ESLD) is liver transplantation (LT). Perioperative management of LT is one of the most challenging issues for anesthesiologists.
Nedim Çekmen, Ahmed Uslu
doaj   +1 more source

Recognition and Management of Hospital-Acquired Sepsis Among Older General Medical Inpatients: A Multi-Site Retrospective Study

International Journal of General Medicine, 2023
Nicholas Barker,1 Ian A Scott,1 Robert Seaton,2 Naitik Mehta,2 Vikrant R Kalke,2 Lyndell Redpath2 1Department of Internal Medicine and Clinical Epidemiology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; 2Patient Quality and Safety ...
Barker N, Scott IA, Seaton R, Mehta N, Kalke VR, Redpath L   +5 more
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source