Results 111 to 120 of about 2,026,223 (341)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The On Track Survey 2011 longitudinal report : the 2007 cohort 4 years on [PDF]
, 2012 This report examines the pathways of young people who left a Victorian government school in 2007. The participants in this On Track longitudinal survey comprised 2346 Year 12 or equivalent completers and 1130 early school leavers. These young people were
Rothman, Sheldon, Underwood, Catherine
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Décrocheurs/raccrocheurs en Irlande
Revue Internationale d’Éducation de Sèvres, 2004 In recent years, the Irish government has implemented measures and provided funding to tackle the problem of early school leavers. The approaches are locally focused and generally take the form of curricular changes and community partnerships.
Scott Boldt
doaj +1 more source
School non-completers: Profiles and initial destinations [PDF]
, 2008 This study examines non-completion of Year 12 at school for a nationally representative sample of young people who were 15 years old and still attending school in 2003.
David D. Curtis, Julie McMillan
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Earning and learning: educational policy and the growth of part-time work by full-time pupils [PDF]
The ‘traditional’ view, in both educational and labour-market policy, of the transition from education to employment centres on the school-leaving decision — in other words, on a particular point in time when the individual concerned decides to leave ...
Christian Dustmann +3 more
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source