Results 1 to 10 of about 278,348 (261)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Rambam Maimonides Medical JournalThe aftermath of the Second World War and the Holocaust triggered mass migration of Jewish refugees to British Mandatory Palestine and, after 1948, the nascent State of Israel. Responding to this crisis, Jews in the Diaspora increased their commitment to
Dorit Weiss
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Social Welfare: Interdisciplinary Approach, 2013 This paper describes a model of professional development for Early Intervention based on an ongoing project taking place in a Midwestern state in the United States of America.
Sanna Harjusola-Webb +2 more
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Cuaderno Urbano, 2021 This article studies the experience of two housing cooperatives, located in the southern area of Rosario city, during the 1980s. The objective of this work is investigate how these organizations were link to the implementation or alternative habitat ...
Anahí G. Pagnoni
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Early Childhood Educational and Care Institutions as Learning Organizations
Journal of Early Childhood Education Research, 2014 Official documents state that all Early Childhood Educational and Care Institutions in Norway should aspire to become learning organizations. In this paper, we analyze governance models in Early Childhood Educational and Care Institutions and look at ...
Berit Irene Vannebo +1 more
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Israel's Relations with Emerging African States
Journal of Central and Eastern European African StudiesIsrael developedits relations with African countries relatively early. The initial boom in the 1950s was followed by a slowdown in the 1960s and then, in many respects, a standstill after the 1973 Yom Kippur War.
Attila Novák
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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