Results 41 to 50 of about 278,348 (261)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
THE STATE BANK OFFICE IN SAMARA REGION AT THE EARLY XX CENTURY: ORGANIZATION OF INTERNAL LIFE
Izvestiya of Samara Scientific Center of the Russian Academy of Sciences. History Sciences, 2021 On the base on archival documents, the author examines the social composition, educational level, and professional competencies of employees of the Samara office of the Russian Empire State Bank from the standpoint of the theory of institutionalism. The study comes to the conclusion about the gradual staff growth in the department, the improvement of ...
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Learning Health Systems, 2021 Introduction Learning health systems (LHSs) are usually created and maintained by single institutions or healthcare systems. The Indiana Learning Health System Initiative (ILHSI) is a new multi‐institutional, collaborative regional LHS initiative led by ...
Titus Schleyer +14 more
doaj +1 more source
Frontiers in Water, 2023 Complex water-stressed basins like the Colorado River in North America have multiple institutional levels of water management. Each institutional level is characterized by rules, organizations, and spatial jurisdictions that developed over decades to ...
James L. Wescoat
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Agricultural Seasonality and the Organization of Manufacturing During Early Industrialization: The Contrast Between Britain and the United States [PDF]
, 1991 The United States differed dramatically from Britain in the way manufacturing was organized during early industrialization. Even before widespread mechanization, American production was almost exclusively from centralized plants, whereas the British and other European economies were characterized by extensive cottage manufacture. This paper argues that
Kenneth L. Sokoloff, David Dollar
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Breaking the boundaries of professional regulation: medical licensing, foreign influence, and the consolidation of homeopathy in Mexico [PDF]
História, Ciências, Saúde: Manguinhos, 2019 As doctors sought state support to regulate professional training and practice after Independence, Mexicans also developed different attitudes toward foreign ideas, influences, and professionals.
Jethro Hernández Berrones
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source