Results 61 to 70 of about 278,348 (261)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

ASSESSMENT OF THE AVAILABILITY OF CT AND MRI STUDIES FOR CANCER PATIENTS IN SAINT-PETERSBURG

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2019
Introduction. The fundamental strategic objective of the national health care was to increase the life expectancy of Russians including the early detection and treatment of cancer, remaining in recent years the leading cause of mortality, and therefore ...
Valeria N. Pospelova   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Morphofunctional state of the immune system organs in hypotrophic piglets in the early neonatal period

open access: yesAgrarian Bulletin of the Urals
Abstract. The purpose of the study was to study the state of the immune system organs in hypotrophic piglets in the early neonatal period in an industrial pig breeding complex. Methods. The experiment was conducted in 2023 in a large industrial pig farm in the Voronezh region on piglets of the wounded neonatal period received from sows 3-4 farrowing ...
B. V. Shabunin   +3 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Jewish Community of Irkutsk in 1917 - the Late 1930s

open access: yesRUDN Journal of Russian History
The authors examine the history of the early Soviet period (1917 - late 1930s) of the Jewish community of Irkutsk, which by the beginning of the 20th century was the largest Jewish community in Siberia. The fate of the main choral synagogue, three houses
Elena A. Berman, Elena S. Genina
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

MORALE AND DISCIPLINE OF THE SOVIET POLICE OFFICERS IN THE LATE 1940s – EARLY 1950s (on archival materials of the Sverdlovsk region)

open access: yesЭлектронное приложение к Российскому юридическому журналу, 2019
The article is based on unpublished archival materials of the Center for Documentation of Public Organizations of the Sverdlovsk Region. The author examines the internal state of the Soviet police in the post-war period.
Mamyachenkov Vladimir
doaj   +1 more source

Home - About - Disclaimer - Privacy