Results 81 to 90 of about 22,736,691 (304)

ASSESSMENT OF THE AVAILABILITY OF CT AND MRI STUDIES FOR CANCER PATIENTS IN SAINT-PETERSBURG

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2019
Introduction. The fundamental strategic objective of the national health care was to increase the life expectancy of Russians including the early detection and treatment of cancer, remaining in recent years the leading cause of mortality, and therefore ...
Valeria N. Pospelova, Boris A. Minko, Svetlana M. Gelbutovskaya, Egor A. Strogonov   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Jewish Community of Irkutsk in 1917 - the Late 1930s

RUDN Journal of Russian History
The authors examine the history of the early Soviet period (1917 - late 1930s) of the Jewish community of Irkutsk, which by the beginning of the 20th century was the largest Jewish community in Siberia. The fate of the main choral synagogue, three houses
Elena A. Berman, Elena S. Genina
doaj   +1 more source

Morphofunctional state of the immune system organs in hypotrophic piglets in the early neonatal period

Agrarian Bulletin of the Urals
Abstract. The purpose of the study was to study the state of the immune system organs in hypotrophic piglets in the early neonatal period in an industrial pig breeding complex. Methods. The experiment was conducted in 2023 in a large industrial pig farm in the Voronezh region on piglets of the wounded neonatal period received from sows 3-4 farrowing ...
B. V. Shabunin, A. V. Nekrasov, E. M. Stepanov, E. V. Mikhaylov   +3 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Year ... of the Oregon Early Childhood Equity Fund evaluation report summary. Spanish

, 2021
Began with Year 1 (2021).Subtitles vary.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

The Directions of Educational Activities of Polish Organizations in West Prussia in the Late Nineteenth and Early Twentieth Century

Studia Paedagogica Ignatiana, 2016
The development of the Polish national movement in West Prussia began with the Spring of Nations. In the face of the Germanization policy of the authorities, Prussian Poles began to create their own organizations designed to maintain Polish identity and ...
Paweł Śpica
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

MORALE AND DISCIPLINE OF THE SOVIET POLICE OFFICERS IN THE LATE 1940s – EARLY 1950s (on archival materials of the Sverdlovsk region)

Электронное приложение к Российскому юридическому журналу, 2019
The article is based on unpublished archival materials of the Center for Documentation of Public Organizations of the Sverdlovsk Region. The author examines the internal state of the Soviet police in the post-war period.
Mamyachenkov Vladimir
doaj   +1 more source