Results 81 to 90 of about 1,825,336 (309)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
ASSESSMENT OF THE AVAILABILITY OF CT AND MRI STUDIES FOR CANCER PATIENTS IN SAINT-PETERSBURG
Introduction. The fundamental strategic objective of the national health care was to increase the life expectancy of Russians including the early detection and treatment of cancer, remaining in recent years the leading cause of mortality, and therefore ...
Valeria N. Pospelova +3 more
doaj +1 more source
Managing Invasive Species: How Much Do We Spend? [PDF]
Invasive species: they’re along roadways and up mountain trails; they’re in lakes and along the coast; chances are they’re in your yard. You might not recognize them for what they are—plants or animals not native to Alaska, brought here accidentally or
Alaska SeaLife Center +3 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Abstract. The purpose of the study was to study the state of the immune system organs in hypotrophic piglets in the early neonatal period in an industrial pig breeding complex. Methods. The experiment was conducted in 2023 in a large industrial pig farm in the Voronezh region on piglets of the wounded neonatal period received from sows 3-4 farrowing ...
B. V. Shabunin +3 more
openaire +2 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Union Leadership Development as Driver of Equity and Inclusion [PDF]
Analysis generated for the research project on Young Workers and the Labor Movement highlighted the need for innovative leadership development if young workers are to be integrated into an increasingly diverse workers’ movement, and unleashed to provide ...
Alvarez, Jose F, Alvarez, Sally
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Jewish Community of Irkutsk in 1917 - the Late 1930s
The authors examine the history of the early Soviet period (1917 - late 1930s) of the Jewish community of Irkutsk, which by the beginning of the 20th century was the largest Jewish community in Siberia. The fate of the main choral synagogue, three houses
Elena A. Berman, Elena S. Genina
doaj +1 more source
McKnight Foundation - 2003 Annual Report: 50 Years - The Common Thread [PDF]
Contains board chair's message, president's message, program information, grant and project highlights, financial statements, list of board members and staff, and nine essays that trace the 50-year history of the ...
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